doi:10.3389/ijph.2022.1604913engLear-Claveras, AnaOliván-Blázquez, BárbaraClavería, AnaCouso-Viana, SabelaPuente-Comesaña, JesúsMagallón Botaya, RosaSex Differences in Clinical Parameters, Pharmacological and Health-Resource Utilization in a Population With Hypertension Without a Diagnosis of COVID-19ART-2022-130610Objectives: Determine the changes in clinical, pharmacological and healthcare resource use parameters, between the 6 months prior to the lockdown and the 6 months following its end, in a population with hypertension who did not have a diagnosis of COVID-19.Methods: Real world data observational study of 245,979 persons aged >16 years with hypertension in Aragon (Spain). Clinical (systolic-diastolic blood pressure, estimated glomerular filtration rate (eGFR), blood creatinine, cholesterol, triglycerides and anthropometric measures); pharmacological (diuretics, calcium channel antagonists, and ACE inhibitors); and utilization of healthcare resources were considered. We performed the Student’s T-test for matched samples (quantitative) and the Chi-squared test (qualitative) to analyze differences between periods.Results: SBP, DBP, parameters of renal function and triglycerides displayed a significant, albeit clinically irrelevant, worsening in women. In men only DBP and eGFR showed a worsening, although to a lesser extent than in women. Certain antihypertensive drugs and health-resource utilization remained below pre-pandemic levels across the 6 months post-lockdown.Conclusion: Changes in lifestyles, along with difficulties in access to routine care has not substantially compromised the health and quality of life of patients with hypertension.2022http://zaguan.unizar.es/record/12017810.3389/ijph.2022.1604913http://zaguan.unizar.es/record/120178oai:zaguan.unizar.es:120178info:eu-repo/grantAgreement/ES/ISCIII-RICAPPS/RD21-0016-0005info:eu-repo/grantAgreement/ES/ISCIII-RICAPPS/RD21-0022International Journal of Public Health 67 (2022), 1604913 [10 pp.]byhttp://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccess