120208 20240319081019.0 doi 10.3390/ani12233341 sideral 131048 ART-2022-131048 eng Villanueva-Saz, Sergio Universidad de Zaragoza (orcid)0000-0001-6209-4282 Anaemia in Sheep Caused by Babesia and Theileria Haemoparasites 2022 Access copy available to the general public Unrestricted Piroplasmoses in sheep are caused by vector-borne apicomplexan protozoa, Babesia and Theileria. Different species are responsible for the disease; some species are more pathogenic than others and have a worldwide distribution. In this sense, these causative agents can cause anaemia in flocks. In general, these vector-borne diseases infect small ruminants and cause host-mediated pathology. In the case of Babesia species, a combination of different mechanisms is involved: red blood cell lysis due to intracellular parasite multiplication, activation of biogenic amines and the coagulation system with the possibility of disseminated intravascular coagulation. By contrast, less information is available on the different immunopathogenic mechanisms involved in the development of anaemia in sheep with theileriosis. However, the mechanisms of pathogenic action in theileriosis are similar to those studied in babesiosis. Diagnosis is based on compatible clinical signs, laboratory findings, specific diagnostic tests and the presence of the tick vector. Some of these tests detect the causative agent itself, such as direct identification by light microscopy and molecular analysis. In contrast, other tests detect the sheep’s immune response to the organism by serology. Both diseases pose a significant diagnostic challenge for veterinary practitioners around the world. This review presents the most frequent clinical signs, pathogenesis and clinicopathological findings, diagnosis. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.0 2022 VETERINARY SCIENCES 13 / 144 = 0.09 2022 Q1 T1 AGRICULTURE, DAIRY & ANIMAL SCIENCE 12 / 62 = 0.194 2022 Q1 T1 0.684 2022 Veterinary (miscellaneous) 2022 Q1 Animal Science and Zoology 2022 Q1 4.2 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Borobia, Marta Universidad de Zaragoza (orcid)0000-0002-0680-9957 Fernández, Antonio Universidad de Zaragoza (orcid)0000-0002-2557-4890 Jiménez, Calasanz Yzuel, Andrés Verde, María Teresa Universidad de Zaragoza (orcid)0000-0003-2957-1379 Ramo, María Ángeles Universidad de Zaragoza (orcid)0000-0002-6282-5038 Figueras, Luis Universidad de Zaragoza (orcid)0000-0002-5477-8534 Ruíz, Héctor Universidad de Zaragoza (orcid)0000-0002-8474-2831 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 12, 23 (2022), 3341 [15 pp.] Animals (Basel) Animals 2076-2615 2133868 http://zaguan.unizar.es/record/120208/files/texto_completo.pdf Versión publicada 2685036 http://zaguan.unizar.es/record/120208/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:120208 articulos driver 2024-03-18-16:01:38 ARTICLE