Editorial: Mechanobiology and the microenvironment: Computational and experimental approaches

Mak, M. ; Carlier, A. ; Spill, F. ; Malandrino, A. ; Long, Mian ; Gomez-Benito, M. J. (Universidad de Zaragoza)

Resumen: The cell microenvironment (ME) varies among a wide range of tissues and influences critical cell processes such as proliferation, differentiation, migration and matrix production. It has been demonstrated that extracellular matrix (ECM) mechanical properties (i.e., stiffness, viscoelasticity (Mierke et al.), adhesiveness and topography) and the mechanical state of the ME influence the outcome of these cellular processes. In recent years, the influence of the ME on cancer progression has been the focus of extensive research. However, how local cell-ME interactions influence tissue level processes, such as vasculogenesis (Edgar et al.; Hermans et al.; Karayaka et al.), tissue morphogenesis (Karayaka et al.) and bone healing and remodelling (Ledoux et al.; Paul et al.), has been understudied. In this research topic collection, exciting new studies shed light on the relationship between the mechanobiology of these processes and the ME, using experimental and computational techniques...

Idioma: Inglés

DOI: 10.3389/fcell.2022.1054135

Año: 2022

Publicado en: Frontiers in Cell and Developmental Biology 10 (2022), 1054135[3 pp.]
ISSN: 2296-634X

Factor impacto JCR: 5.5 (2022)

Categ. JCR: DEVELOPMENTAL BIOLOGY rank: 5 / 39 = 0.128 (2022) - Q1 - T1
Categ. JCR: CELL BIOLOGY rank: 66 / 191 = 0.346 (2022) - Q2 - T2

Factor impacto CITESCORE: 6.3 - Biochemistry, Genetics and Molecular Biology (Q2)

Factor impacto SCIMAGO: 1.418 - Developmental Biology (Q1) - Cell Biology (Q2)

Financiación: info:eu-repo/grantAgreement/ES/MICINN/PID2021-124271OB-I00

Tipo y forma: (Versión definitiva)

Área (Departamento): Área Mec.Med.Cont. y Teor.Est. (Dpto. Ingeniería Mecánica)