120964 20240319081014.0 doi 10.3390/ani12243454 sideral 131072 ART-2022-131072 eng Ramo, María de los Angeles Universidad de Zaragoza (orcid)0000-0002-6282-5038 Coxiella burnetii and Co-Infections with Other Major Pathogens Causing Abortion in Small Ruminant Flocks in the Iberian Peninsula 2022 Access copy available to the general public Unrestricted Coxiella burnetii is an intracellular bacterium causing human Q fever and reproductive disorders in domestic ruminants. We analyzed the occurrence of C. burnetii and co-infections with six other major pathogens causing abortion in sheep (1242 cases) and goat (371 cases) flocks from Spain and Portugal. After real-time PCR detection, co-infections were established by principal component and cluster analysis that grouped cases based on the joint presence/absence of several microorganisms. C. burnetii and Chlamydia abortus were the most common abortifacient agents with approximately 75% of cases from both hosts testing positive, followed by Toxoplasma gondii, Campylobacter sp., Salmonella enterica, border disease virus and Neospora caninum. C. burnetii was significantly more common than C. abortus in goat abortions (p < 0.001). Co-infections with at least two pathogens were found in more than 66% cases of ovine abortions and 36% cases of caprine abortions testing positive for C. burnetii, mostly including mixed infections with only C. abortus. These findings indicate that both pathogens are the most significant ones to be readily prevented by vaccination in this geographical area. Biosecurity and biocontainment measures are also steadfastly recommended to prevent both the economic losses and public health risks associated with most of these abortifacient agents. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.0 2022 VETERINARY SCIENCES 13 / 144 = 0.09 2022 Q1 T1 AGRICULTURE, DAIRY & ANIMAL SCIENCE 12 / 62 = 0.194 2022 Q1 T1 0.684 2022 Veterinary (miscellaneous) 2022 Q1 Animal Science and Zoology 2022 Q1 4.2 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Benito, Alfredo A. Quílez, Joaquín Universidad de Zaragoza (orcid)0000-0001-7831-2483 Monteagudo, Luis V. Universidad de Zaragoza (orcid)0000-0003-0210-2919 Baselga, Cristina Tejedor, María Teresa Universidad de Zaragoza (orcid)0000-0001-5026-5144 1001 420 Universidad de Zaragoza Dpto. Anatom.,Embri.Genét.Ani. Área Genética 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 12, 24 (2022), 3454 [15 pp.] Animals (Basel) Animals 2076-2615 358782 http://zaguan.unizar.es/record/120964/files/texto_completo.pdf Versión publicada 2754517 http://zaguan.unizar.es/record/120964/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:120964 articulos driver 2024-03-18-15:27:33 ARTICLE