121012 20241125101128.0 doi 10.1111/jgh.16033 sideral 131249 ART-2023-131249 eng Lanas, Angel Universidad de Zaragoza (orcid)0000-0001-5932-2889 Management of iron-deficiency anemia following acute gastrointestinal hemorrhage: A narrative analysis and review 2023 Access copy available to the general public Unrestricted Many patients experiencing acute gastrointestinal bleeding (GIB) require iron supplemen-tation to treat subsequent iron deficiency (ID) or iron-deficiency anemia (IDA). Guidelinesregarding management of these patients are lacking. We aimed to identify areas of unmetneed in patients with ID/IDA following acute GIB in terms of patient management andphysician guidance. We formed an international working group of gastroenterologists toconduct a narrative review based on PubMed and EMBASE database searches (fromJanuary 2000 to February 2021), integrated with observations from our own clinical expe-rience. Published data on this subject are limited and disparate, and those relating topost-discharge outcomes, such as persistent anemia and re-hospitalization, are particularlylacking. Often, there is no post-discharge follow-up of these patients by a gastroenterolo-gist. Acute GIB-related ID/IDA, however, is a prevalent condition both at the time of hos-pital admission and at hospital discharge and is likely underdiagnosed and undertreated.Despite limited data, there appears to be notable variation in the prescribing of intravenous(IV)/oral iron regimens. There is also some evidence suggesting that, compared with oraliron, IV iron may restore iron levels faster following acute GIB, have a better tolerabilityprofile, and be more beneficial in terms of quality of life. Gaps in patient care exist inthe management of acute GIB-related ID/IDA, yet further data from largepopulation-based studies are needed to confirm this. We advocate the formulation ofevidence-based guidance on the use of iron therapies in these patients, aiding a more stan-dardized best-practice approach to patient care. info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 3.7 2023 GASTROENTEROLOGY & HEPATOLOGY 40 / 143 = 0.28 2023 Q2 T1 1.179 2023 Gastroenterology 2023 Q1 Hepatology 2023 Q2 7.9 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Andrews, Jane M Lau, James Toruner, Murat Bromley, Susan E Gralnek, Ian M 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 38, 1 (2023), 23-33 J. gastroenterol. hepatol. Journal of Gastroenterology and Hepatology (Australia) 0815-9319 233563 http://zaguan.unizar.es/record/121012/files/texto_completo.pdf Versión publicada 2668967 http://zaguan.unizar.es/record/121012/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:121012 articulos driver 2024-11-22-11:58:13 ARTICLE