000121068 001__ 121068
000121068 005__ 20240319080948.0
000121068 0247_ $$2doi$$a10.1002/smi.3088
000121068 0248_ $$2sideral$$a125890
000121068 037__ $$aART-2022-125890
000121068 041__ $$aeng
000121068 100__ $$aMontoliu T.
000121068 245__ $$aMediation of perceived stress and cortisol in the association between neuroticism and global cognition in older adults: A longitudinal study
000121068 260__ $$c2022
000121068 5060_ $$aAccess copy available to the general public$$fUnrestricted
000121068 5203_ $$aNeuroticism has been associated with a greater dementia risk, but its association with cognitive decline in healthy older adults remains unclear. Stress has been proposed as one of the mechanisms that could explain this relationship. Our aim was to analyse, in healthy older people, the mediating role of perceived stress and the Hypothalamic–Pituitary–Adrenal (HPA) axis in the association between neuroticism and global cognition. At Waves 1 and 2 (4-year follow-up), 87 older people (49.4% women; M age = 65.08, SD = 4.54 at Wave 1) completed a neuropsychological battery and the Perceived Stress Scale (PSS), and provided saliva samples on two (Wave 1) and three (Wave 2) consecutive days to measure the wake-to-bed slope. In Wave 2, neuroticism was assessed with the NEO-Five-Factor Inventory. PSS, but not the wake-to-bed slope, mediated the negative associations between neuroticism and global cognition (Waves 1, 2 and change). Regarding gender differences, PSS (Waves 1, 2 and change) and the wake-to-bed slope (Wave 2 and change) mediated these associations in men. Our results suggest that perceived stress and HPA-axis dysregulation could act as mechanisms underlying the association between neuroticism and cognitive functioning and decline, at least in older men. © 2021. The Authors. Stress and Health published by John Wiley & Sons Ltd.
000121068 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/Construyendo Europa desde Aragón$$9info:eu-repo/grantAgreement/ES/DGA-FEDER/S31-20D$$9info:eu-repo/grantAgreement/ES/MEC/PSI2013-46889$$9info:eu-repo/grantAgreement/ES/MEC/PSI2016-78763
000121068 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000121068 590__ $$a4.1$$b2022
000121068 592__ $$a1.196$$b2022
000121068 591__ $$aPSYCHOLOGY$$b17 / 81 = 0.21$$c2022$$dQ1$$eT1
000121068 593__ $$aApplied Psychology$$c2022$$dQ1
000121068 591__ $$aPSYCHOLOGY, APPLIED$$b26 / 83 = 0.313$$c2022$$dQ2$$eT1
000121068 593__ $$aPsychiatry and Mental Health$$c2022$$dQ1
000121068 591__ $$aPSYCHIATRY$$b49 / 143 = 0.343$$c2022$$dQ2$$eT2
000121068 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000121068 591__ $$aPSYCHIATRY$$b66 / 154 = 0.429$$c2022$$dQ2$$eT2
000121068 593__ $$aClinical Psychology$$c2022$$dQ1
000121068 594__ $$a5.4$$b2022
000121068 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000121068 700__ $$0(orcid)0000-0002-7048-3795$$aPulopulos M.M.$$uUniversidad de Zaragoza
000121068 700__ $$aPuig-Pérez S.
000121068 700__ $$0(orcid)0000-0003-3920-1099$$aHidalgo V.$$uUniversidad de Zaragoza
000121068 700__ $$aSalvador A.
000121068 7102_ $$14009$$2725$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicobiología
000121068 773__ $$g38, 2 (2022), 290-303$$pStress health$$tStress and Health$$x1532-3005
000121068 8564_ $$s709794$$uhttps://zaguan.unizar.es/record/121068/files/texto_completo.pdf$$yVersión publicada
000121068 8564_ $$s2189724$$uhttps://zaguan.unizar.es/record/121068/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000121068 909CO $$ooai:zaguan.unizar.es:121068$$particulos$$pdriver
000121068 951__ $$a2024-03-18-12:45:05
000121068 980__ $$aARTICLE