000121102 001__ 121102
000121102 005__ 20240319081000.0
000121102 0247_ $$2doi$$a10.1002/adfm.202106932
000121102 0248_ $$2sideral$$a126278
000121102 037__ $$aART-2022-126278
000121102 041__ $$aeng
000121102 100__ $$0(orcid)0000-0002-4678-7465$$aUson, L.
000121102 245__ $$aNanoengineering palladium plasmonic nanosheets inside polymer nanospheres for photothermal therapy and targeted drug delivery
000121102 260__ $$c2022
000121102 5060_ $$aAccess copy available to the general public$$fUnrestricted
000121102 5203_ $$aThe incorporation of plasmonic nanoconstructs in biodegradable polymeric nanoparticles (NPs), together with therapeutic drugs in a controlled procedure is of interest for different applications in Nanomedicine. Advanced hybrid nanomaterials can be engineered by combining the in situ formation of plasmonic palladium nanosheets (NSs) and the proper ionic nature of the encapsulated drug. This study presents a new procedure to synthesize hybrid nanostructures by a Pickering double emulsion. Anisotropic palladium (Pd) NSs with unique near-infrared (NIR)-optical properties can be assembled within a poly lactic-co-glycolic acid matrix of < 200 nm NPs, when Pd precursors are in situ reduced via a gas-phase procedure. The hybrid nanomaterials respond to external NIR light stimulus. The unprecedented precision to assemble, in a single stage, plasmonic nanoconstructs having a total loading selectivity, when encapsulated in combination with hydrophobic drugs, offers new opportunities in the new class of theragnostics, in particular when triggered drug delivery and photothermal therapies are required.
000121102 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E13-20R$$9info:eu-repo/grantAgreement/EC/FP7/614715/EU/A Photo-triggered On-demand Drug Delivery System for Chronic Pain/NANOHEDONISM$$9info:eu-repo/grantAgreement/EC/H2020/823717/EU/Enabling Science and Technology through European Electron Microscopy/ESTEEM3$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 823717-ESTEEM3$$9info:eu-repo/grantAgreement/ES/ISCIII/MS19-00092$$9info:eu-repo/grantAgreement/ES/MICINN-AEI/PID2019-104739GB-I00/AEI-10.13039-501100011033$$9info:eu-repo/grantAgreement/ES/MICINN/RTI2018-099019-A-I00
000121102 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000121102 590__ $$a19.0$$b2022
000121102 592__ $$a5.565$$b2022
000121102 591__ $$aCHEMISTRY, PHYSICAL$$b10 / 161 = 0.062$$c2022$$dQ1$$eT1
000121102 591__ $$aMATERIALS SCIENCE, MULTIDISCIPLINARY$$b16 / 343 = 0.047$$c2022$$dQ1$$eT1
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000121102 591__ $$aPHYSICS, APPLIED$$b8 / 160 = 0.05$$c2022$$dQ1$$eT1
000121102 593__ $$aBiomaterials$$c2022$$dQ1
000121102 593__ $$aChemistry (miscellaneous)$$c2022$$dQ1
000121102 593__ $$aCondensed Matter Physics$$c2022$$dQ1
000121102 593__ $$aNanoscience and Nanotechnology$$c2022$$dQ1
000121102 593__ $$aElectronic, Optical and Magnetic Materials$$c2022$$dQ1
000121102 593__ $$aMaterials Science (miscellaneous)$$c2022$$dQ1
000121102 593__ $$aElectrochemistry$$c2022$$dQ1
000121102 594__ $$a27.9$$b2022
000121102 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000121102 700__ $$0(orcid)0000-0002-1505-498X$$aYus, C.$$uUniversidad de Zaragoza
000121102 700__ $$aMendoza, G.
000121102 700__ $$aLeroy, E.
000121102 700__ $$0(orcid)0000-0002-2966-9088$$aIrusta, S.$$uUniversidad de Zaragoza
000121102 700__ $$0(orcid)0000-0002-9324-0446$$aAlejo, T.$$uUniversidad de Zaragoza
000121102 700__ $$aGarcía-Domingo, D.
000121102 700__ $$0(orcid)0000-0002-6277-7996$$aLarrea, A.
000121102 700__ $$0(orcid)0000-0003-3165-0156$$aArruebo, M.$$uUniversidad de Zaragoza
000121102 700__ $$0(orcid)0000-0002-2071-9093$$aArenal, R.
000121102 700__ $$0(orcid)0000-0002-6873-5244$$aSebastián, V.$$uUniversidad de Zaragoza
000121102 7102_ $$15005$$2555$$aUniversidad de Zaragoza$$bDpto. Ing.Quím.Tecnol.Med.Amb.$$cÁrea Ingeniería Química
000121102 7102_ $$15005$$2790$$aUniversidad de Zaragoza$$bDpto. Ing.Quím.Tecnol.Med.Amb.$$cÁrea Tecnologi. Medio Ambiente
000121102 773__ $$g32, 9 (2022), 2106932 [14 pp.]$$pAdv. funct. mater.$$tAdvanced Functional Materials$$x1616-301X
000121102 8564_ $$s3759251$$uhttps://zaguan.unizar.es/record/121102/files/texto_completo.pdf$$yVersión publicada
000121102 8564_ $$s2447761$$uhttps://zaguan.unizar.es/record/121102/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
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000121102 951__ $$a2024-03-18-14:06:54
000121102 980__ $$aARTICLE