121102 20240319081000.0 doi 10.1002/adfm.202106932 sideral 126278 ART-2022-126278 eng Uson, L. (orcid)0000-0002-4678-7465 Nanoengineering palladium plasmonic nanosheets inside polymer nanospheres for photothermal therapy and targeted drug delivery 2022 Access copy available to the general public Unrestricted The incorporation of plasmonic nanoconstructs in biodegradable polymeric nanoparticles (NPs), together with therapeutic drugs in a controlled procedure is of interest for different applications in Nanomedicine. Advanced hybrid nanomaterials can be engineered by combining the in situ formation of plasmonic palladium nanosheets (NSs) and the proper ionic nature of the encapsulated drug. This study presents a new procedure to synthesize hybrid nanostructures by a Pickering double emulsion. Anisotropic palladium (Pd) NSs with unique near-infrared (NIR)-optical properties can be assembled within a poly lactic-co-glycolic acid matrix of < 200 nm NPs, when Pd precursors are in situ reduced via a gas-phase procedure. The hybrid nanomaterials respond to external NIR light stimulus. The unprecedented precision to assemble, in a single stage, plasmonic nanoconstructs having a total loading selectivity, when encapsulated in combination with hydrophobic drugs, offers new opportunities in the new class of theragnostics, in particular when triggered drug delivery and photothermal therapies are required. info:eu-repo/grantAgreement/ES/DGA/E13-20R info:eu-repo/grantAgreement/EC/FP7/614715/EU/A Photo-triggered On-demand Drug Delivery System for Chronic Pain/NANOHEDONISM info:eu-repo/grantAgreement/EC/H2020/823717/EU/Enabling Science and Technology through European Electron Microscopy/ESTEEM3 This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 823717-ESTEEM3 info:eu-repo/grantAgreement/ES/ISCIII/MS19-00092 info:eu-repo/grantAgreement/ES/MICINN-AEI/PID2019-104739GB-I00/AEI-10.13039-501100011033 info:eu-repo/grantAgreement/ES/MICINN/RTI2018-099019-A-I00 info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 19.0 2022 CHEMISTRY, PHYSICAL 10 / 161 = 0.062 2022 Q1 T1 MATERIALS SCIENCE, MULTIDISCIPLINARY 16 / 343 = 0.047 2022 Q1 T1 NANOSCIENCE & NANOTECHNOLOGY 9 / 107 = 0.084 2022 Q1 T1 PHYSICS, CONDENSED MATTER 6 / 67 = 0.09 2022 Q1 T1 CHEMISTRY, MULTIDISCIPLINARY 8 / 178 = 0.045 2022 Q1 T1 PHYSICS, APPLIED 8 / 160 = 0.05 2022 Q1 T1 5.565 2022 Biomaterials 2022 Q1 Chemistry (miscellaneous) 2022 Q1 Condensed Matter Physics 2022 Q1 Nanoscience and Nanotechnology 2022 Q1 Electronic, Optical and Magnetic Materials 2022 Q1 Materials Science (miscellaneous) 2022 Q1 Electrochemistry 2022 Q1 27.9 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Yus, C. Universidad de Zaragoza (orcid)0000-0002-1505-498X Mendoza, G. Leroy, E. Irusta, S. Universidad de Zaragoza (orcid)0000-0002-2966-9088 Alejo, T. Universidad de Zaragoza (orcid)0000-0002-9324-0446 García-Domingo, D. Larrea, A. (orcid)0000-0002-6277-7996 Arruebo, M. Universidad de Zaragoza (orcid)0000-0003-3165-0156 Arenal, R. (orcid)0000-0002-2071-9093 Sebastián, V. Universidad de Zaragoza (orcid)0000-0002-6873-5244 5005 555 Universidad de Zaragoza Dpto. Ing.Quím.Tecnol.Med.Amb. Área Ingeniería Química 5005 790 Universidad de Zaragoza Dpto. Ing.Quím.Tecnol.Med.Amb. Área Tecnologi. Medio Ambiente 32, 9 (2022), 2106932 [14 pp.] Adv. funct. mater. Advanced Functional Materials 1616-301X 3759251 http://zaguan.unizar.es/record/121102/files/texto_completo.pdf Versión publicada 2447761 http://zaguan.unizar.es/record/121102/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:121102 articulos driver 2024-03-18-14:06:54 ARTICLE