000121172 001__ 121172
000121172 005__ 20240319081015.0
000121172 0247_ $$2doi$$a10.3390/jcm11247540
000121172 0248_ $$2sideral$$a131823
000121172 037__ $$aART-2022-131823
000121172 041__ $$aeng
000121172 100__ $$aZabana, Yamile
000121172 245__ $$aRisk Factors for COVID-19 in Inflammatory Bowel Disease: A National, ENEIDA-Based Case–Control Study (COVID-19-EII)
000121172 260__ $$c2022
000121172 5060_ $$aAccess copy available to the general public$$fUnrestricted
000121172 5203_ $$a(1) Scant information is available concerning the characteristics that may favour the acquisition of COVID-19 in patients with inflammatory bowel disease (IBD). Therefore, the aim of this study was to assess these differences between infected and noninfected patients with IBD. (2) This nationwide case–control study evaluated patients with inflammatory bowel disease with COVID-19 (cases) and without COVID-19 (controls) during the period March–July 2020 included in the ENEIDA of GETECCU. (3) A total of 496 cases and 964 controls from 73 Spanish centres were included. No differences were found in the basal characteristics between cases and controls. Cases had higher comorbidity Charlson scores (24% vs. 19%; p = 0.02) and occupational risk (28% vs. 10.5%; p < 0.0001) more frequently than did controls. Lockdown was the only protective measure against COVID-19 (50% vs. 70%; p < 0.0001). No differences were found in the use of systemic steroids, immunosuppressants or biologics between cases and controls. Cases were more often treated with 5-aminosalicylates (42% vs. 34%; p = 0.003). Having a moderate Charlson score (OR: 2.7; 95%CI: 1.3–5.9), occupational risk (OR: 2.9; 95%CI: 1.8–4.4) and the use of 5-aminosalicylates (OR: 1.7; 95%CI: 1.2–2.5) were factors for COVID-19. The strict lockdown was the only protective factor (OR: 0.1; 95%CI: 0.09–0.2). (4) Comorbidities and occupational exposure are the most relevant factors for COVID-19 in patients with IBD. The risk of COVID-19 seems not to be increased by immunosuppressants or biologics, with a potential effect of 5-aminosalicylates, which should be investigated further and interpreted with caution.
000121172 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000121172 590__ $$a3.9$$b2022
000121172 592__ $$a0.935$$b2022
000121172 591__ $$aMEDICINE, GENERAL & INTERNAL$$b58 / 169 = 0.343$$c2022$$dQ2$$eT2
000121172 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000121172 594__ $$a5.4$$b2022
000121172 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000121172 700__ $$aMarín-Jiménez, Ignacio
000121172 700__ $$aRodríguez-Lago, Iago
000121172 700__ $$aVera, Isabel
000121172 700__ $$aMartín-Arranz, María Dolores
000121172 700__ $$aGuerra, Iván
000121172 700__ $$aP. Gisbert, Javier
000121172 700__ $$aMesonero, Francisco
000121172 700__ $$aBenítez, Olga
000121172 700__ $$aTaxonera, Carlos
000121172 700__ $$aPonferrada-Díaz, Ángel
000121172 700__ $$aPiqueras, Marta
000121172 700__ $$aJ. Lucendo, Alfredo
000121172 700__ $$aCaballol, Berta
000121172 700__ $$aMañosa, Míriam
000121172 700__ $$aMartínez-Montiel, Pilar
000121172 700__ $$aBosca-Watts, Maia
000121172 700__ $$aGordillo, Jordi
000121172 700__ $$aBujanda, Luis
000121172 700__ $$aManceñido, Noemí
000121172 700__ $$aMartínez-Pérez, Teresa
000121172 700__ $$aLópez, Alicia
000121172 700__ $$aRodríguez-Gutiérrez, Cristina
000121172 700__ $$0(orcid)0000-0003-3970-5457$$aGarcía-López, Santiago$$uUniversidad de Zaragoza
000121172 700__ $$aVega, Pablo
000121172 700__ $$aRivero, Montserrat
000121172 700__ $$aMelcarne, Luigi
000121172 700__ $$aCalvo, María
000121172 700__ $$aIborra, Marisa
000121172 700__ $$aBarreiro de Acosta, Manuel
000121172 700__ $$aSicilia, Beatriz
000121172 700__ $$aBarrio, Jesús
000121172 700__ $$aPérez Calle, José Lázaro
000121172 700__ $$aBusquets, David
000121172 700__ $$aPérez-Martínez, Isabel
000121172 700__ $$aNavarro-Llavat, Mercè
000121172 700__ $$aHernández, Vicent
000121172 700__ $$aArgüelles-Arias, Federico
000121172 700__ $$aRamírez Esteso, Fernando
000121172 700__ $$aMeijide, Susana
000121172 700__ $$aRamos, Laura
000121172 700__ $$0(orcid)0000-0003-0076-3529$$aGomollón, Fernando$$uUniversidad de Zaragoza
000121172 700__ $$aMuñoz, Fernando
000121172 700__ $$aSuris, Gerard
000121172 700__ $$aOrtiz de Zarate, Jone
000121172 700__ $$aHuguet, José María
000121172 700__ $$aLlaó, Jordina
000121172 700__ $$aGarcía-Sepulcre, Mariana Fe
000121172 700__ $$aSierra, Mónica
000121172 700__ $$aDurà, Miguel
000121172 700__ $$aEstrecha, Sandra
000121172 700__ $$aFuentes Coronel, Ana
000121172 700__ $$aHinojosa, Esther
000121172 700__ $$aOlivan, Lorenzo
000121172 700__ $$aIglesias, Eva
000121172 700__ $$aGutiérrez, Ana
000121172 700__ $$aVarela, Pilar
000121172 700__ $$aRull, Núria
000121172 700__ $$aGilabert, Pau
000121172 700__ $$aHernández-Camba, Alejandro
000121172 700__ $$aBrotons, Alicia
000121172 700__ $$aGinard, Daniel
000121172 700__ $$aSesé, Eva
000121172 700__ $$aCarpio, Daniel
000121172 700__ $$aAceituno, Montserrat
000121172 700__ $$aCabriada, José Luis
000121172 700__ $$aGonzález-Lama, Yago
000121172 700__ $$aJiménez, Laura
000121172 700__ $$aChaparro, María
000121172 700__ $$aLópez-San Román, Antonio
000121172 700__ $$aAlba, Cristina
000121172 700__ $$aPlaza-Santos, Rocío
000121172 700__ $$aMena, Raquel
000121172 700__ $$aTamarit-Sebastián, Sonsoles
000121172 700__ $$aRicart, Elena
000121172 700__ $$aCalafat, Margalida
000121172 700__ $$aOlivares, Sonsoles
000121172 700__ $$aNavarro, Pablo
000121172 700__ $$aBertoletti, Federico
000121172 700__ $$aAlonso-Galán, Horacio
000121172 700__ $$aPajares, Ramón
000121172 700__ $$aOlcina, Pablo
000121172 700__ $$aManzano, Pamela
000121172 700__ $$aDomènech, Eugeni
000121172 700__ $$aEsteve, Maria
000121172 700__ $$a
000121172 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000121172 773__ $$g11, 24 (2022), 7540 [14 pp.]$$pJ. clin.med.$$tJournal of Clinical Medicine$$x2077-0383
000121172 8564_ $$s633454$$uhttps://zaguan.unizar.es/record/121172/files/texto_completo.pdf$$yVersión publicada
000121172 8564_ $$s2849516$$uhttps://zaguan.unizar.es/record/121172/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
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000121172 951__ $$a2024-03-18-15:34:44
000121172 980__ $$aARTICLE