121172 20240319081015.0 doi 10.3390/jcm11247540 sideral 131823 ART-2022-131823 eng Zabana, Yamile Risk Factors for COVID-19 in Inflammatory Bowel Disease: A National, ENEIDA-Based Case–Control Study (COVID-19-EII) 2022 Access copy available to the general public Unrestricted (1) Scant information is available concerning the characteristics that may favour the acquisition of COVID-19 in patients with inflammatory bowel disease (IBD). Therefore, the aim of this study was to assess these differences between infected and noninfected patients with IBD. (2) This nationwide case–control study evaluated patients with inflammatory bowel disease with COVID-19 (cases) and without COVID-19 (controls) during the period March–July 2020 included in the ENEIDA of GETECCU. (3) A total of 496 cases and 964 controls from 73 Spanish centres were included. No differences were found in the basal characteristics between cases and controls. Cases had higher comorbidity Charlson scores (24% vs. 19%; p = 0.02) and occupational risk (28% vs. 10.5%; p < 0.0001) more frequently than did controls. Lockdown was the only protective measure against COVID-19 (50% vs. 70%; p < 0.0001). No differences were found in the use of systemic steroids, immunosuppressants or biologics between cases and controls. Cases were more often treated with 5-aminosalicylates (42% vs. 34%; p = 0.003). Having a moderate Charlson score (OR: 2.7; 95%CI: 1.3–5.9), occupational risk (OR: 2.9; 95%CI: 1.8–4.4) and the use of 5-aminosalicylates (OR: 1.7; 95%CI: 1.2–2.5) were factors for COVID-19. The strict lockdown was the only protective factor (OR: 0.1; 95%CI: 0.09–0.2). (4) Comorbidities and occupational exposure are the most relevant factors for COVID-19 in patients with IBD. The risk of COVID-19 seems not to be increased by immunosuppressants or biologics, with a potential effect of 5-aminosalicylates, which should be investigated further and interpreted with caution. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.9 2022 MEDICINE, GENERAL & INTERNAL 58 / 169 = 0.343 2022 Q2 T2 0.935 2022 Medicine (miscellaneous) 2022 Q1 5.4 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Marín-Jiménez, Ignacio Rodríguez-Lago, Iago Vera, Isabel Martín-Arranz, María Dolores Guerra, Iván P. Gisbert, Javier Mesonero, Francisco Benítez, Olga Taxonera, Carlos Ponferrada-Díaz, Ángel Piqueras, Marta J. Lucendo, Alfredo Caballol, Berta Mañosa, Míriam Martínez-Montiel, Pilar Bosca-Watts, Maia Gordillo, Jordi Bujanda, Luis Manceñido, Noemí Martínez-Pérez, Teresa López, Alicia Rodríguez-Gutiérrez, Cristina García-López, Santiago Universidad de Zaragoza (orcid)0000-0003-3970-5457 Vega, Pablo Rivero, Montserrat Melcarne, Luigi Calvo, María Iborra, Marisa Barreiro de Acosta, Manuel Sicilia, Beatriz Barrio, Jesús Pérez Calle, José Lázaro Busquets, David Pérez-Martínez, Isabel Navarro-Llavat, Mercè Hernández, Vicent Argüelles-Arias, Federico Ramírez Esteso, Fernando Meijide, Susana Ramos, Laura Gomollón, Fernando Universidad de Zaragoza (orcid)0000-0003-0076-3529 Muñoz, Fernando Suris, Gerard Ortiz de Zarate, Jone Huguet, José María Llaó, Jordina García-Sepulcre, Mariana Fe Sierra, Mónica Durà, Miguel Estrecha, Sandra Fuentes Coronel, Ana Hinojosa, Esther Olivan, Lorenzo Iglesias, Eva Gutiérrez, Ana Varela, Pilar Rull, Núria Gilabert, Pau Hernández-Camba, Alejandro Brotons, Alicia Ginard, Daniel Sesé, Eva Carpio, Daniel Aceituno, Montserrat Cabriada, José Luis González-Lama, Yago Jiménez, Laura Chaparro, María López-San Román, Antonio Alba, Cristina Plaza-Santos, Rocío Mena, Raquel Tamarit-Sebastián, Sonsoles Ricart, Elena Calafat, Margalida Olivares, Sonsoles Navarro, Pablo Bertoletti, Federico Alonso-Galán, Horacio Pajares, Ramón Olcina, Pablo Manzano, Pamela Domènech, Eugeni Esteve, Maria 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 11, 24 (2022), 7540 [14 pp.] J. clin.med. Journal of Clinical Medicine 2077-0383 633454 http://zaguan.unizar.es/record/121172/files/texto_completo.pdf Versión publicada 2849516 http://zaguan.unizar.es/record/121172/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:121172 articulos driver 2024-03-18-15:34:44 ARTICLE