121233 20240319081024.0 doi 10.1016/j.epidem.2022.100633 sideral 131854 ART-2022-131854 eng Santos, Nuno Complementary roles of wild boar and red deer to animal tuberculosis maintenance in multi-host communities 2022 Access copy available to the general public Unrestricted The contribution of wildlife species to pathogen maintenance in multi-host communities has seldom been quantified. To assess the relative contribution of the main wildlife hosts of animal tuberculosis (TB) to its maintenance, we estimated the basic reproduction number (R0) of Mycobacterium tuberculosis complex in wild boar and red deer at 29 sites in the Iberian Peninsula. Host abundance and true TB prevalence were estimated for each species at each site by sampling from distributions incorporating the uncertainty in the proportion of the population harvested each year, sensitivity, and specificity of the diagnostic methods, while excretion of mycobacteria was estimated using site-occupancy models. The distributions of these parameters were then used to estimate, at each site, the R0,wild boar (range 0.1 – 55.9, average 8.7, standard deviation 11.8), and the R0,red deer (0.1 – 18.9, 2.2, 3.9). Animal TB is maintained in epidemiological scenarios ranging from any single species acting as a maintenance host (the wild boar in 18 sites and the red deer in 5), to facultative multi-host disease (6 sites). The prevalence of TB in the red deer is likely an important driver of the epidemiology in multi-host communities. The wild boar was the main maintenance host of TB in most of the study sites and could have an epidemiological role linking the wildlife multi-host community and livestock. info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 3.8 2022 INFECTIOUS DISEASES 49 / 96 = 0.51 2022 Q3 T2 1.448 2022 Epidemiology 2022 Q1 Infectious Diseases 2022 Q1 Microbiology 2022 Q1 Parasitology 2022 Q1 Public Health, Environmental and Occupational Health 2022 Q1 Virology 2022 Q2 6.5 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Colino, Elisa Ferreras Arnal, María Cruz Universidad de Zaragoza (orcid)0000-0002-6770-3400 Fernández de Luco, Daniel Universidad de Zaragoza (orcid)0000-0003-3289-4267 Sevilla, Iker Garrido, Joseba M. Fonseca, Eliana Valente, Ana M. Balseiro, Ana Queirós, João Almeida, Virgílio Vicente, Joaquín Gortázar, Christian Alves, Paulo Célio 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 41 (2022), 100633 [11 pp.] EPIDEMICS EPIDEMICS 1755-4365 5125877 http://zaguan.unizar.es/record/121233/files/texto_completo.pdf Versión publicada 2383139 http://zaguan.unizar.es/record/121233/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:121233 articulos driver 2024-03-18-16:32:28 ARTICLE