121379 20230914083656.0 doi 10.1515/almed-2022-0107 sideral 131892 ART-2022-131892 eng Lasierra Monclús, Ana Belén Universidad de Zaragoza Effects of the COVID-19 pandemic on the activity of clinical laboratories in Spain, evolution in the 2019–2021 period 2022 Access copy available to the general public Unrestricted Objectives. To assess the impact of the COVID-19 pandemic on the activity of clinical laboratories in Spain. Methods. A descriptive, observational, retrospective, multicenter study. Results. Between March and December 2020, there was a statistically significant decrease in the number of test requests (−17.7%, p=<0.001) and total tests performed (−18.3%, p<0.001) with respect to the same period in 2019. A decrease was observed in the number of requests from primary care (−37.4%) (p<0.001) and in the number of foecal occult blood (−45.8%); qualitative urine (−30.1%); PSA (−28.5%); TSH (−27.8%); total cholesterol (−27.2%) and HbA1c (−24.7%) tests performed, p<0.001. A significant increase was found in the number of requests from ICUs (76.6%, p<0.001) and number of IL-6 (+22,350.9), D-dimer (+617.2%), troponin (+46.8%) and arterial blood gas (+3.9%) tests carried out, p<0.001. During the first months of 2021, there were significant changes in the number of requests for qualitative urine (−8.7%, p<0.001), PSA (−6.3%, p=0.009), IL-6 (+66,269.2, p<0.001), D-dimer (+603.6%, p<0.001), troponin (+28.7%, p<0.001), arterial blood gas (+26,2%, p=0.014) and ferritin (+16.0%, p=0.002) tests performed. Conclusions. There were changes in the origin and number of test requested to clinical laboratories in Spain. The number of requests for the evaluation and monitoring of COVID-19 patients increased, whereas requests for the control of non-COVID patients and for population screening decreased. Long-term analysis reveals that the volume of tests performed for the control of chronic diseases returned to normal over time, whereas the increase observed in the volume of tests performed for the management of COVID-19 patients is maintained. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 0.199 2022 Medical Laboratory Technology 2022 Q3 Medicine (miscellaneous) 2022 Q4 Education 2022 Q4 0.7 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion González, Álvaro Bernabéu Andreu, Francisco A. Caballé Martín, Imma Buño Soto, Antonio Ibarz, Mercè González Rodríguez, Concepción Puzo Foncillas, José Universidad de Zaragoza (orcid)0000-0002-1309-4363 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 3, 4 (2022), 361-370 Adv. lab. med Advances in laboratory medicine 2628-491X 1461451 http://zaguan.unizar.es/record/121379/files/texto_completo.pdf Versión publicada 2760792 http://zaguan.unizar.es/record/121379/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:121379 articulos driver 2023-09-13-14:18:59 ARTICLE