000121383 001__ 121383
000121383 005__ 20240319081019.0
000121383 0247_ $$2doi$$a10.24820/ark.5550190.p011.804
000121383 0248_ $$2sideral$$a131933
000121383 037__ $$aART-2022-131933
000121383 041__ $$aeng
000121383 100__ $$aSempere, Inmaculada
000121383 245__ $$aDiastereoselective deacylative aldol reaction 
of 3-acetyl-3-fluorooxindoles with aldehydes
000121383 260__ $$c2022
000121383 5060_ $$aAccess copy available to the general public$$fUnrestricted
000121383 5203_ $$aThe deacetylative aldol reaction of N-methyl-3-acetyl-3-fluoro-2-oxindole is optimized with benzaldehyde and the most appropriate conditions are used for the survey of the scope of this transformation with different aldehydes. The relative configuration of the resulting compounds is also confirmed. The reaction is diastereoselective and affords the syn-stereoisomer in good yields. DFT calculations are used for the explanation of this diastereoselectivity through a traditional chair-like transition state.
000121383 536__ $$9info:eu-repo/grantAgreement/ES/AEI-MINECO-FEDER/CTQ2016-76782-P$$9info:eu-repo/grantAgreement/ES/AEI-MINECO-FEDER/CTQ2016-80375-P$$9info:eu-repo/grantAgreement/ES/MICINN/RED2018-102387-T$$9info:eu-repo/grantAgreement/ES/MINECO-AEI-FEDER/CTQ2017-82935-P$$9info:eu-repo/grantAgreement/ES/MINECO-FEDER/PID2019-104090RB-100$$9info:eu-repo/grantAgreement/ES/MINECO-FEDER/PID2019-107268GB-I00
000121383 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000121383 590__ $$a0.9$$b2022
000121383 592__ $$a0.182$$b2022
000121383 591__ $$aCHEMISTRY, ORGANIC$$b44 / 52 = 0.846$$c2022$$dQ4$$eT3
000121383 593__ $$aOrganic Chemistry$$c2022$$dQ4
000121383 594__ $$a1.0$$b2022
000121383 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000121383 700__ $$aMolina, Cynthia
000121383 700__ $$aGarcía-Mingüens, Eduardo
000121383 700__ $$aRetamosa, Mª de Gracia
000121383 700__ $$aNájera, Carmen
000121383 700__ $$0(orcid)0000-0002-2202-3460$$aMerino, Pedro$$uUniversidad de Zaragoza
000121383 700__ $$aYus, Miguel
000121383 700__ $$aSansano, José M.
000121383 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000121383 773__ $$g2023, 3 (2022), 16-32$$pARKIVOC$$tARKIVOC$$x1551-7004
000121383 8564_ $$s752519$$uhttps://zaguan.unizar.es/record/121383/files/texto_completo.pdf$$yVersión publicada
000121383 8564_ $$s1679294$$uhttps://zaguan.unizar.es/record/121383/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000121383 909CO $$ooai:zaguan.unizar.es:121383$$particulos$$pdriver
000121383 951__ $$a2024-03-18-15:59:56
000121383 980__ $$aARTICLE