000121387 001__ 121387 000121387 005__ 20240122154816.0 000121387 0247_ $$2doi$$a10.3390/ijerph18116042 000121387 0248_ $$2sideral$$a131739 000121387 037__ $$aART-2021-131739 000121387 041__ $$aeng 000121387 100__ $$0(orcid)0000-0002-6829-0775$$aPradas, Francisco$$uUniversidad de Zaragoza 000121387 245__ $$aEffects of padel competition on brain health-related myokines 000121387 260__ $$c2021 000121387 5060_ $$aAccess copy available to the general public$$fUnrestricted 000121387 5203_ $$aPadel is becoming one of the most widespread racket sports that may have potential health benefits. Considering that several myokines mediate the cross-talk between skeletal muscles and the brain, exerting positive effects on brain health status, this study was designed to evaluate the responses of brain-derived neurotrophic factor (BDNF), leukemia inhibitory factor (LIF), and irisin (IR) to padel competition in trained players and to determine whether these responses were sex-dependent. Twenty-four trained padel players (14 women and 10 men with a mean age of 27.8 ± 6.3 years) participated voluntarily in this study. Circulating levels of BDNF, LIF, and IR were assessed before and after simulated padel competition (real playing time, 27.8 ± 8.49 min; relative intensity, 75.2 ± 7.9% maximum heart rate). Except for BDNF responses observed in female players (increasing from 1531.12 ± 269.09 to 1768.56 ± 410.75 ng/mL), no significant changes in LIF and IR concentrations were reported after padel competition. In addition, no sex-related differences were found. Moreover, significant associations between IR and BDNF were established at both pre- and post-competition. Our results suggest that while competitive padel practice stimulates BDNF response in female players, padel competition failed to boost the release of LIF and IR. Future studies are needed to further explore the role of these exercise-induced myokines in the regulation of brain functions and to identify the field sports that can contribute to myokine-mediated muscle–brain crosstalk. 000121387 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000121387 590__ $$a4.614$$b2021 000121387 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b45 / 182 = 0.247$$c2021$$dQ1$$eT1 000121387 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b71 / 210 = 0.338$$c2021$$dQ2$$eT2 000121387 591__ $$aENVIRONMENTAL SCIENCES$$b100 / 279 = 0.358$$c2021$$dQ2$$eT2 000121387 592__ $$a0.814$$b2021 000121387 593__ $$aPollution$$c2021$$dQ1 000121387 593__ $$aHealth, Toxicology and Mutagenesis$$c2021$$dQ1 000121387 594__ $$a4.5$$b2021 000121387 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000121387 700__ $$aCádiz, María Pía 000121387 700__ $$aNestares, María Teresa 000121387 700__ $$aMartínez-Díaz, Inmaculada C. 000121387 700__ $$aCarrasco, Luis 000121387 7102_ $$13001$$2187$$aUniversidad de Zaragoza$$bDpto. Expres.Music.Plást.Corp.$$cÁrea Didáctica Expres.Corporal 000121387 773__ $$g18, 11 (2021), 6042 [11 pp]$$pInt. j. environ. res. public health$$tInternational journal of environmental research and public health$$x1661-7827 000121387 8564_ $$s1027567$$uhttps://zaguan.unizar.es/record/121387/files/texto_completo.pdf$$yVersión publicada 000121387 8564_ $$s2781210$$uhttps://zaguan.unizar.es/record/121387/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000121387 909CO $$ooai:zaguan.unizar.es:121387$$particulos$$pdriver 000121387 951__ $$a2024-01-22-15:42:34 000121387 980__ $$aARTICLE