000121396 001__ 121396
000121396 005__ 20240319081020.0
000121396 0247_ $$2doi$$a10.1080/14767058.2022.2051008
000121396 0248_ $$2sideral$$a132123
000121396 037__ $$aART-2022-132123
000121396 041__ $$aeng
000121396 100__ $$0(orcid)0000-0002-2801-416X$$aPérez-López, Faustino R.
000121396 245__ $$aObstetric and perinatal outcomes of pregnancies with COVID 19: a systematic review and meta-analysis
000121396 260__ $$c2022
000121396 5060_ $$aAccess copy available to the general public$$fUnrestricted
000121396 5203_ $$aObjective.
This meta-analysis aimed at comparing obstetric and perinatal outcomes in laboratory-tested pregnant women for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection before delivering.
Method.
We performed a comprehensive systematic review of electronic databases for studies reporting pregnant women with and without SARS-CoV-2 infection, as determined by polymerase chain reaction (PCR) before delivery, during the pandemic period published up to June 25, 2021. Results are reported as mean difference (MD) or odds ratio (OR) and their 95% confidence interval (CI).
Results.
Seventeen observational studies with low to moderate risk of bias, reported on 2,769 pregnant women with a positive SARS-CoV-2 PCR test and 13,807 with a negative test. Pregnant women with a positive PCR test delivered at an earlier gestational age (MD −0.19; 95% CI −0.36 to −0.02 weeks), smoked less (OR 0.75; 95% CI 0.61–0.94) and were associated with higher odds for preeclampsia (OR 1.30; 95% CI 1.09–1.54), NICU admissions (OR 2.37; 95% CI 1.18–4.76), stillbirths (OR 2.70; 95% CI, 1.38–5.29), and perinatal mortality (OR 3.23; 95% CI 1.23–8.52). There were no significant differences between positive and negative tested women in terms of nulliparity, multiple pregnancies, gestational diabetes, route of delivery, labor induction, preterm birth, infant birth weight, 5 min Apgar scores < 7, small-for-gestational-age infants and fetal malformations. Eleven studies included neonatal PCR SARS-CoV-2 testing which was performed on 129 infants, of which 20 were positive.
Conclusion.
Positive SARS-CoV-2 tested pregnant women had higher odds for preeclampsia/hypertensive disorders of pregnancy, NICU admissions, stillbirths and perinatal mortality.
000121396 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000121396 590__ $$a1.8$$b2022
000121396 592__ $$a0.664$$b2022
000121396 591__ $$aOBSTETRICS & GYNECOLOGY$$b67 / 85 = 0.788$$c2022$$dQ4$$eT3
000121396 593__ $$aPediatrics, Perinatology and Child Health$$c2022$$dQ2
000121396 593__ $$aObstetrics and Gynecology$$c2022$$dQ2
000121396 594__ $$a3.9$$b2022
000121396 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000121396 700__ $$0(orcid)0000-0001-9585-0187$$aSavirón-Cornudella, Ricardo$$uUniversidad de Zaragoza
000121396 700__ $$aChedraui, Peter
000121396 700__ $$aLópez-Baena, María T.
000121396 700__ $$aPérez-Roncero, Gonzalo$$uUniversidad de Zaragoza
000121396 700__ $$aSanz-Arenal, Ana
000121396 700__ $$aNarváez-Salazar, Marta
000121396 700__ $$aDieste-Pérez, Peña
000121396 700__ $$0(orcid)0000-0003-4720-8231$$aTajada, Mauricio$$uUniversidad de Zaragoza
000121396 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000121396 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana
000121396 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología
000121396 773__ $$g35, 25 (2022), 9742-9758$$pJ. matern.-fetal neonatal med.$$tJournal of Maternal-Fetal and Neonatal Medicine$$x1476-7058
000121396 8564_ $$s5971941$$uhttps://zaguan.unizar.es/record/121396/files/texto_completo.pdf$$yVersión publicada
000121396 8564_ $$s1195534$$uhttps://zaguan.unizar.es/record/121396/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000121396 909CO $$ooai:zaguan.unizar.es:121396$$particulos$$pdriver
000121396 951__ $$a2024-03-18-16:05:12
000121396 980__ $$aARTICLE