000123878 001__ 123878 000123878 005__ 20240319081028.0 000123878 0247_ $$2doi$$a10.3390/antibiotics11121746 000123878 0248_ $$2sideral$$a132387 000123878 037__ $$aART-2022-132387 000123878 041__ $$aeng 000123878 100__ $$aAlfaro, Enrique$$uUniversidad de Zaragoza 000123878 245__ $$aEvaluation of different strategies to improve the management of Helicobacter Pylori infection at the primary care level: training sessions increase prescription appropriateness of treatment regimens 000123878 260__ $$c2022 000123878 5060_ $$aAccess copy available to the general public$$fUnrestricted 000123878 5203_ $$aHelicobacter pylori infection (H. pylori) is mainly managed at the primary care level. Our group previously performed a study demonstrating that providing specific counselling (SC) to primary care practitioners (PCPs) who requested a urea breath test (UBT) improved treatment management but not indications for H. pylori tests. SC was given in the form of a personal letter addressed to PCPs with UBT results which contained information about accepted UBT indications and a Helicobacter pylori treatment algorithm. The purpose of the present study was to evaluate the effect of training sessions (TS) on UBT indications, antibiotic prescriptions and eradication rates. This was a quasi-experimental study performed at primary care centres (PCCs). Phase I included 399 patients diagnosed with H. pylori infection after providing SC to PCPs. Phase II included 400 H. pylori-positive patients after giving TS to PCPs who had already received SC (100 from PCCs with TS and 300 from PCCs without TS). An improved trend in the appropriate indication of H. pylori diagnosis was observed between Phase I and PCCs with TS in Phase II (57.5% vs. 67%; p = 0.06). TS improved appropriate prescriptions in PCCs with TS compared to PCCs that only received SC in Phase I and II (94% vs. 75.3%, p = 0.01; 94% vs. 85.6%, p = 0.04, respectively). Eradication rates showed no differences between groups. In conclusion, training sessions after specific counselling improved antibiotic prescription appropriateness but not eradication rates. 000123878 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000123878 590__ $$a4.8$$b2022 000123878 592__ $$a0.792$$b2022 000123878 591__ $$aPHARMACOLOGY & PHARMACY$$b65 / 278 = 0.234$$c2022$$dQ1$$eT1 000123878 593__ $$aPharmacology, Toxicology and Pharmaceutics (miscellaneous)$$c2022$$dQ1 000123878 591__ $$aINFECTIOUS DISEASES$$b35 / 96 = 0.365$$c2022$$dQ2$$eT2 000123878 593__ $$aInfectious Diseases$$c2022$$dQ2 000123878 593__ $$aMicrobiology (medical)$$c2022$$dQ2 000123878 593__ $$aPharmacology (medical)$$c2022$$dQ2 000123878 593__ $$aBiochemistry$$c2022$$dQ2 000123878 593__ $$aMicrobiology$$c2022$$dQ2 000123878 594__ $$a5.5$$b2022 000123878 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000123878 700__ $$aMartínez-Domínguez, Samuel J.$$uUniversidad de Zaragoza 000123878 700__ $$aLaredo, Viviana$$uUniversidad de Zaragoza 000123878 700__ $$0(orcid)0000-0001-5932-2889$$aLanas, Ángel$$uUniversidad de Zaragoza 000123878 700__ $$0(orcid)0000-0001-7466-3876$$aSostres, Carlos$$uUniversidad de Zaragoza 000123878 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000123878 773__ $$g11, 12 (2022), 1746 [10 pp.]$$pAntibiotics$$tAntibiotics$$x2079-6382 000123878 8564_ $$s1574302$$uhttps://zaguan.unizar.es/record/123878/files/texto_completo.pdf$$yVersión publicada 000123878 8564_ $$s2835317$$uhttps://zaguan.unizar.es/record/123878/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000123878 909CO $$ooai:zaguan.unizar.es:123878$$particulos$$pdriver 000123878 951__ $$a2024-03-18-16:55:59 000123878 980__ $$aARTICLE