000123880 001__ 123880 000123880 005__ 20240319081028.0 000123880 0247_ $$2doi$$a10.3390/diagnostics12123078 000123880 0248_ $$2sideral$$a132403 000123880 037__ $$aART-2022-132403 000123880 041__ $$aeng 000123880 100__ $$aGarcía Gómez de Segura, Mikel 000123880 245__ $$aEvaluation of Macular Thickness Changes after Uncomplicated Phacoemulsification Surgery in Healthy Subjects and Diabetic Patients without Retinopathy by Spectral Domain OCT 000123880 260__ $$c2022 000123880 5060_ $$aAccess copy available to the general public$$fUnrestricted 000123880 5203_ $$aPurpose: To assess differences in the evolution of macular thickness after uncomplicated phacoemulsification surgery between non-diabetic subjects and patients with diabetes mellitus (DM) without diabetic retinopathy (DR), using Spectral Domain OCT (SD-OCT). Methods: We performed a unicentric prospective study including one hundred and thirty-one eyes of 70 patients divided into two groups—34 well-controlled DM patients without DR and 36 non-diabetic subjects—who underwent phacoemulsification for cataract surgery. Eyes that developed pseudophakic cystoid macular edema (PCME) were excluded from the study, leaving us with 64 patients. Macular thickness was analyzed using Cirrus HD-OCT (Macular Cube 512 × 128 protocol) preoperatively and on postoperative days 7, 30, 90, and 180. For cases with information available for both eyes, one eye was randomly selected for analysis. Results: A total of 64 eyes from 64 patients were analyzed in this study. The mean value of HbA1c in the diabetic group was 7%. After uncomplicated cataract surgery, patients showed no increase of the foveal, parafoveal, and perifoveal retinal thickness on postoperative day 7. However, thickness values increased on days 30, 90, and 180 after surgery in both groups, and peak at 90 days. There was no difference in macular thickness before or after surgery between DM and non-diabetic patients (p = 0.540). Conclusion: Macular thickness increases up to 6 months after uncomplicated cataract surgery in both DM patients without DR and non-diabetic subjects, with no differences between increases in both groups. 000123880 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000123880 590__ $$a3.6$$b2022 000123880 592__ $$a0.67$$b2022 000123880 591__ $$aMEDICINE, GENERAL & INTERNAL$$b64 / 169 = 0.379$$c2022$$dQ2$$eT2 000123880 593__ $$aClinical Biochemistry$$c2022$$dQ2 000123880 594__ $$a3.6$$b2022 000123880 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000123880 700__ $$aMartín-Arroyuelos, Ana 000123880 700__ $$0(orcid)0000-0003-0349-9997$$aPinilla, Isabel$$uUniversidad de Zaragoza 000123880 700__ $$aAraiz, Javier 000123880 7102_ $$11013$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Oftalmología 000123880 773__ $$g12, 12 (2022), 3078 [12 pp.]$$tDiagnostics$$x2075-4418 000123880 8564_ $$s4269730$$uhttps://zaguan.unizar.es/record/123880/files/texto_completo.pdf$$yVersión publicada 000123880 8564_ $$s2805400$$uhttps://zaguan.unizar.es/record/123880/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000123880 909CO $$ooai:zaguan.unizar.es:123880$$particulos$$pdriver 000123880 951__ $$a2024-03-18-16:56:04 000123880 980__ $$aARTICLE