000123902 001__ 123902
000123902 005__ 20230216104024.0
000123902 0247_ $$2doi$$a10.3390/w15010014
000123902 0248_ $$2sideral$$a132395
000123902 037__ $$aART-2023-132395
000123902 041__ $$aeng
000123902 100__ $$aGozzo, Sebastiano
000123902 245__ $$aScreening for antibiotics and their degradation products in surface and wastewaters of the POCTEFA territory by solid-phase Extraction-UPLC-Electrospray MS/MS
000123902 260__ $$c2023
000123902 5060_ $$aAccess copy available to the general public$$fUnrestricted
000123902 5203_ $$aA method based on UPLC-MS/MS (ultraperformance liquid chromatography—tandem mass spectrometry) was optimized for the analysis of a broad set of antibiotics and their metabolites in surface and wastewaters after their preconcentration by solid-phase extraction (SPE). The method was applied to the monitoring of the river basin of the POCTEFA (Interregional Programme Spain-France-Andorra) territory (Spain and France) in frame of a sampling campaign (2020–2021) including 40 sampling points, 28 of them corresponding to surface waters and 12 to wastewaters. In total, 21 antibiotics belonging to different families, i.e., ciprofloxacin, sulfamethoxazole, trimethoprim, azithromycin, and their metabolites were detected. A higher overall antibiotic contamination was observed in the Spanish part of the POCTEFA territory. Several metabolites of the target antibiotics, some of them supposed to be more toxic than their parent compounds, were identified in the entire sampling network. Fluoroquinolones and sulfamethoxazole, as well as their metabolites, presented the highest detection frequency both in wastewaters and surface waters, and, consequently, should be considered as target compounds in the monitoring of the water resources of the POCTEFA territory.
000123902 536__ $$9info:eu-repo/grantAgreement/EUR/INTERREG-V-POCTEFA-2014-2020
000123902 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000123902 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000123902 700__ $$0(orcid)0000-0002-1401-7511$$aMoles, Samuel$$uUniversidad de Zaragoza
000123902 700__ $$aKinska, Katarzyna
000123902 700__ $$0(orcid)0000-0003-3014-0322$$aOrmad, Maria P.$$uUniversidad de Zaragoza
000123902 700__ $$0(orcid)0000-0002-7456-4912$$aMosteo, Rosa$$uUniversidad de Zaragoza
000123902 700__ $$aGómez, Jairo
000123902 700__ $$0(orcid)0000-0002-4169-0357$$aLaborda, Francisco$$uUniversidad de Zaragoza
000123902 700__ $$aSzpunar, Joanna
000123902 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica
000123902 7102_ $$15005$$2790$$aUniversidad de Zaragoza$$bDpto. Ing.Quím.Tecnol.Med.Amb.$$cÁrea Tecnologi. Medio Ambiente
000123902 773__ $$g15, 1 (2023), 14 [19 pp]$$pWater (Basel)$$tWater (Switzerland)$$x2073-4441
000123902 8564_ $$s2288806$$uhttps://zaguan.unizar.es/record/123902/files/texto_completo.pdf$$yVersión publicada
000123902 8564_ $$s2784824$$uhttps://zaguan.unizar.es/record/123902/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000123902 909CO $$ooai:zaguan.unizar.es:123902$$particulos$$pdriver
000123902 951__ $$a2023-02-16-08:49:59
000123902 980__ $$aARTICLE