123902 20241125101129.0 doi 10.3390/w15010014 sideral 132395 ART-2023-132395 eng Gozzo, Sebastiano Screening for antibiotics and their degradation products in surface and wastewaters of the POCTEFA territory by solid-phase Extraction-UPLC-Electrospray MS/MS 2023 Access copy available to the general public Unrestricted A method based on UPLC-MS/MS (ultraperformance liquid chromatography—tandem mass spectrometry) was optimized for the analysis of a broad set of antibiotics and their metabolites in surface and wastewaters after their preconcentration by solid-phase extraction (SPE). The method was applied to the monitoring of the river basin of the POCTEFA (Interregional Programme Spain-France-Andorra) territory (Spain and France) in frame of a sampling campaign (2020–2021) including 40 sampling points, 28 of them corresponding to surface waters and 12 to wastewaters. In total, 21 antibiotics belonging to different families, i.e., ciprofloxacin, sulfamethoxazole, trimethoprim, azithromycin, and their metabolites were detected. A higher overall antibiotic contamination was observed in the Spanish part of the POCTEFA territory. Several metabolites of the target antibiotics, some of them supposed to be more toxic than their parent compounds, were identified in the entire sampling network. Fluoroquinolones and sulfamethoxazole, as well as their metabolites, presented the highest detection frequency both in wastewaters and surface waters, and, consequently, should be considered as target compounds in the monitoring of the water resources of the POCTEFA territory. info:eu-repo/grantAgreement/EUR/INTERREG-V-POCTEFA-2014-2020 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.0 2023 WATER RESOURCES 40 / 128 = 0.312 2023 Q2 T1 ENVIRONMENTAL SCIENCES 169 / 358 = 0.472 2023 Q2 T2 0.724 2023 Aquatic Science 2023 Q1 Water Science and Technology 2023 Q1 Geography, Planning and Development 2023 Q1 Biochemistry 2023 Q2 5.8 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Moles, Samuel Universidad de Zaragoza (orcid)0000-0002-1401-7511 Kinska, Katarzyna Ormad, Maria P. Universidad de Zaragoza (orcid)0000-0003-3014-0322 Mosteo, Rosa Universidad de Zaragoza (orcid)0000-0002-7456-4912 Gómez, Jairo Laborda, Francisco Universidad de Zaragoza (orcid)0000-0002-4169-0357 Szpunar, Joanna 2009 750 Universidad de Zaragoza Dpto. Química Analítica Área Química Analítica 5005 790 Universidad de Zaragoza Dpto. Ing.Quím.Tecnol.Med.Amb. Área Tecnologi. Medio Ambiente 15, 1 (2023), 14 [19 pp] Water (Basel) Water (Switzerland) 2073-4441 2288806 http://zaguan.unizar.es/record/123902/files/texto_completo.pdf Versión publicada 2784824 http://zaguan.unizar.es/record/123902/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:123902 articulos driver 2024-11-22-11:58:33 ARTICLE