| Home > Articles > Dose–response association of handgrip strength and risk of depression: a longitudinal study of 115 601 older adults from 24 countries > MARC |
000123988 001__ 123988 000123988 005__ 20241125101129.0 000123988 0247_ $$2doi$$a10.1192/bjp.2022.178 000123988 0248_ $$2sideral$$a132586 000123988 037__ $$aART-2023-132586 000123988 041__ $$aeng 000123988 100__ $$0(orcid)0000-0002-7865-3429$$aLópez-Bueno, Rubén 000123988 245__ $$aDose–response association of handgrip strength and risk of depression: a longitudinal study of 115 601 older adults from 24 countries 000123988 260__ $$c2023 000123988 5060_ $$aAccess copy available to the general public$$fUnrestricted 000123988 5203_ $$aBackground: Prior research has solely focused on the association between handgrip strength and risk of depression in single countries or general populations, but more knowledge is required from wider-spread cohorts and target populations. Aims: This study aimed to investigate the association between handgrip strength and risk of depression using repeated measures in adults aged 50 years and over. Method: Data on handgrip strength and risk of depression were retrieved from the Survey of Health, Ageing and Retirement in Europe (SHARE) waves 1, 2, 4, 5, 6 and 7, using a hand dynamometer (Smedley, S Dynamometer, TTM) and the EURO-D 12-item scale, respectively. Time-varying exposure and covariates were modelled using both Cox regression and restricted cubic splines. Results: A total of 115 601 participants (mean age 64.3 years (s.d. = 9.9), 54.3% women) were followed-up for a median of 7.3 years (interquartile range: 3.9–11.8) and 792 459 person-years. During this period, 30 208 (26.1%) participants experienced a risk of depression. When modelled as a continuous variable, we observed an inverse significant association for each kg increase of handgrip strength and depression up to 40 kg in men and up to 27 kg in women. Conclusions: Being physically strong may serve as a preventive factor for depression in older adults, but this is limited up to a maximum specific threshold for men and women. 000123988 536__ $$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 870628-SHARE-COHESION$$9info:eu-repo/grantAgreement/EC/H2020/870628/EU/Cohesion in further developing and innovating SHARE across all 28 member countries/SHARE-COHESION$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 823782-SSHOC$$9info:eu-repo/grantAgreement/EC/H2020/823782/EU/Social Sciences & Humanities Open Cloud/SSHOC$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 676536-SHARE-DEV3$$9info:eu-repo/grantAgreement/EC/H2020/676536/EU/Achieving world-class standards in all SHARE countries/SHARE-DEV3$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 654221-SERISS$$9info:eu-repo/grantAgreement/EC/H2020/654221/EU/Synergies for Europe's Research Infrastructures in the Social Sciences/SERISS$$9info:eu-repo/grantAgreement/EC/HS/QLK6-CT-2001-00360/EU/Survey on health, ageing and retirement in europe (SHARE)/SHARE$$9info:eu-repo/grantAgreement/EC/FP7/283646/EU/Data Service Infrastructure for the Social Sciences and Humanities/DASISH$$9info:eu-repo/grantAgreement/EC/FP7/261982/EU/Multinational Advancement of Research Infrastructures on Ageing/SHARE_M4$$9info:eu-repo/grantAgreement/EC/FP7/227822/EU/Longitudinal Enhancement and Access imProvement of the SHARE infrastructure/SHARE_LEAP$$9info:eu-repo/grantAgreement/EC/FP7/211909/EU/Upgrading the Survey of Health, Ageing and Retirement in Europe – preparatory phase/SHARE-PREP$$9info:eu-repo/grantAgreement/EC/FP6/62193/EU/Survey of Health, Ageing and Retirement in Europe: Integrating Activities to Access the Time Dimension and to Enlarge the Cross-national Dimension/SHARE-I3$$9info:eu-repo/grantAgreement/EC/FP6/28857/EU/Toolbox for Improving the Comparability of Cross-National Survey Data with Applications to SHARE/COMPARE$$9info:eu-repo/grantAgreement/EC/FP6/28812/EU/Employment and health at 50+: a life history approach to european welfare state interventions/SHARELIFE 000123988 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000123988 590__ $$a8.8$$b2023 000123988 591__ $$aPSYCHIATRY$$b10 / 279 = 0.036$$c2023$$dQ1$$eT1 000123988 591__ $$aPSYCHIATRY$$b10 / 279 = 0.036$$c2023$$dQ1$$eT1 000123988 594__ $$a13.7$$b2023 000123988 592__ $$a2.717$$b2023 000123988 593__ $$aPsychiatry and Mental Health$$c2023$$dQ1 000123988 593__ $$aMedicine (miscellaneous)$$c2023$$dQ1 000123988 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000123988 700__ $$aCalatayud, J. 000123988 700__ $$aAndersen, L.L. 000123988 700__ $$aCasaña, J. 000123988 700__ $$aKoyanagi, A. 000123988 700__ $$aDel Pozo Cruz, B. 000123988 700__ $$aSmith, L. 000123988 773__ $$g222, 3 (2023), 135-142$$pBr. j. psychiatry$$tBRITISH JOURNAL OF PSYCHIATRY$$x0007-1250 000123988 8564_ $$s583497$$uhttps://zaguan.unizar.es/record/123988/files/texto_completo.pdf$$yVersión publicada 000123988 8564_ $$s3177591$$uhttps://zaguan.unizar.es/record/123988/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000123988 909CO $$ooai:zaguan.unizar.es:123988$$particulos$$pdriver 000123988 951__ $$a2024-11-22-11:58:28 000123988 980__ $$aARTICLE
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