000125279 001__ 125279
000125279 005__ 20240731103358.0
000125279 0247_ $$2doi$$a10.3390/ijerph20065161
000125279 0248_ $$2sideral$$a132951
000125279 037__ $$aART-2023-132951
000125279 041__ $$aeng
000125279 100__ $$aLavalle, Raffaele
000125279 245__ $$aThe impact of COVID-19 lockdown on adults with major depressive disorder from Catalonia: a decentralized longitudinal study
000125279 260__ $$c2023
000125279 5060_ $$aAccess copy available to the general public$$fUnrestricted
000125279 5203_ $$aThe present study analyzes the effects of each containment phase of the first COVID-19 wave on depression levels in a cohort of 121 adults with a history of major depressive disorder (MDD) from Catalonia recruited from 1 November 2019, to 16 October 2020. This analysis is part of the Remote Assessment of Disease and Relapse-MDD (RADAR-MDD) study. Depression was evaluated with the Patient Health Questionnaire-8 (PHQ-8), and anxiety was evaluated with the Generalized Anxiety Disorder-7 (GAD-7). Depression’s levels were explored across the phases (pre-lockdown, lockdown, and four post-lockdown phases) according to the restrictions of Spanish/Catalan governments. Then, a mixed model was fitted to estimate how depression varied over the phases. A significant rise in depression severity was found during the lockdown and phase 0 (early post-lockdown), compared with the pre-lockdown. Those with low pre-lockdown depression experienced an increase in depression severity during the “new normality”, while those with high pre-lockdown depression decreased compared with the pre-lockdown. These findings suggest that COVID-19 restrictions affected the depression level depending on their pre-lockdown depression severity. Individuals with low levels of depression are more reactive to external stimuli than those with more severe depression, so the lockdown may have worse detrimental effects on them.
000125279 536__ $$9info:eu-repo/grantAgreement/EC/H2020/115902/EU/Remote Assessment of Disease and Relapse in Central Nervous System Disorders/RADAR-CNS$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 115902-RADAR-CNS
000125279 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000125279 592__ $$a0.808$$b2023
000125279 593__ $$aHealth, Toxicology and Mutagenesis$$c2023$$dQ2
000125279 593__ $$aPublic Health, Environmental and Occupational Health$$c2023$$dQ2
000125279 593__ $$aPollution$$c2023$$dQ2
000125279 594__ $$a7.3$$b2023
000125279 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000125279 700__ $$aCondominas, Elena
000125279 700__ $$aHaro, Josep Maria
000125279 700__ $$aGiné-Vázquez, Iago
000125279 700__ $$0(orcid)0000-0003-1272-0550$$aBailon, Raquel$$uUniversidad de Zaragoza
000125279 700__ $$aLaporta, Estela
000125279 700__ $$aGarcia, Ester
000125279 700__ $$0(orcid)0000-0002-1297-0691$$aKontaxis, Spyridon$$uUniversidad de Zaragoza
000125279 700__ $$aRiquelme Alacid, Gemma
000125279 700__ $$aLombardini, Federica
000125279 700__ $$aPreti, Antonio
000125279 700__ $$aPeñarrubia-Maria, Maria Teresa
000125279 700__ $$aCoromina, Marta
000125279 700__ $$aArranz, Belén
000125279 700__ $$aVilella, Elisabet
000125279 700__ $$aRubio-Alacid, Elena
000125279 700__ $$aMatcham, Faith
000125279 700__ $$aLamers, Femke
000125279 700__ $$aHotopf, Matthew
000125279 700__ $$aPenninx, Brenda W. J. H.
000125279 700__ $$aAnnas, Peter
000125279 700__ $$aNarayan, Vaibhav
000125279 700__ $$aSimblett, Sara K.
000125279 700__ $$aSiddi, Sara
000125279 700__ $$aRADAR-CNS Consortium
000125279 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac.
000125279 773__ $$g20, 6 (2023), 5161 [15 pp.]$$pInt. j. environ. res. public health$$tInternational journal of environmental research and public health$$x1661-7827
000125279 8564_ $$s1365966$$uhttps://zaguan.unizar.es/record/125279/files/texto_completo.pdf$$yVersión publicada
000125279 8564_ $$s2887357$$uhttps://zaguan.unizar.es/record/125279/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000125279 909CO $$ooai:zaguan.unizar.es:125279$$particulos$$pdriver
000125279 951__ $$a2024-07-31-09:57:46
000125279 980__ $$aARTICLE