000125281 001__ 125281
000125281 005__ 20241125101150.0
000125281 0247_ $$2doi$$a10.3390/nano13060963
000125281 0248_ $$2sideral$$a132955
000125281 037__ $$aART-2023-132955
000125281 041__ $$aeng
000125281 100__ $$aMagazzù, Alessandro
000125281 245__ $$aInvestigation of soft matter nanomechanics by atomic force microscopy and optical tweezers: a comprehensive review
000125281 260__ $$c2023
000125281 5060_ $$aAccess copy available to the general public$$fUnrestricted
000125281 5203_ $$aSoft matter exhibits a multitude of intrinsic physico-chemical attributes. Their mechanical properties are crucial characteristics to define their performance. In this context, the rigidity of these systems under exerted load forces is covered by the field of biomechanics. Moreover, cellular transduction processes which are involved in health and disease conditions are significantly affected by exogenous biomechanical actions. In this framework, atomic force microscopy (AFM) and optical tweezers (OT) can play an important role to determine the biomechanical parameters of the investigated systems at the single-molecule level. This review aims to fully comprehend the interplay between mechanical forces and soft matter systems. In particular, we outline the capabilities of AFM and OT compared to other classical bulk techniques to determine nanomechanical parameters such as Young’s modulus. We also provide some recent examples of nanomechanical measurements performed using AFM and OT in hydrogels, biopolymers and cellular systems, among others. We expect the present manuscript will aid potential readers and stakeholders to fully understand the potential applications of AFM and OT to soft matter systems.
000125281 536__ $$9info:eu-repo/grantAgreement/ES/CSIC/QTP-2103003
000125281 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000125281 590__ $$a4.4$$b2023
000125281 592__ $$a0.798$$b2023
000125281 591__ $$aMATERIALS SCIENCE, MULTIDISCIPLINARY$$b146 / 439 = 0.333$$c2023$$dQ2$$eT2
000125281 593__ $$aChemical Engineering (miscellaneous)$$c2023$$dQ1
000125281 591__ $$aNANOSCIENCE & NANOTECHNOLOGY$$b62 / 141 = 0.44$$c2023$$dQ2$$eT2
000125281 593__ $$aMaterials Science (miscellaneous)$$c2023$$dQ2
000125281 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b70 / 231 = 0.303$$c2023$$dQ2$$eT1
000125281 591__ $$aPHYSICS, APPLIED$$b47 / 179 = 0.263$$c2023$$dQ2$$eT1
000125281 594__ $$a8.5$$b2023
000125281 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000125281 700__ $$0(orcid)0000-0003-3459-8605$$aMarcuello, Carlos
000125281 773__ $$g13, 6 (2023), 963 [31 pp.]$$pNanomaterials (Basel)$$tNanomaterials$$x2079-4991
000125281 8564_ $$s3658217$$uhttps://zaguan.unizar.es/record/125281/files/texto_completo.pdf$$yVersión publicada
000125281 8564_ $$s2642441$$uhttps://zaguan.unizar.es/record/125281/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000125281 909CO $$ooai:zaguan.unizar.es:125281$$particulos$$pdriver
000125281 951__ $$a2024-11-22-12:06:19
000125281 980__ $$aARTICLE