Not just sensitization: sympathetic mechanisms contribute to expand experimental referred pain

Doménech-García, Victor ; Rubio Peirotén, Alberto ; Lecea Imaz, Miren ; Palsson, T. S. ; Herrero, Pablo (Universidad de Zaragoza) ; Bellosta-López, Pablo

Resumen: Background: Widespread pain partially depends upon sensitization of central pain mechanisms. However, mechanisms controlling pain distribution are not completely known. The present study sought to assess skin temperature variations in the area of experimentally-induced pain and potential sex differences. Methods: Pressure-pain thresholds (PPTs) were measured on the right infraspinatus muscle. At the end of Day 0, all participants performed an eccentric exercise of the shoulder external rotators to induce muscle soreness 24 hours after. On Day 1, participants indicated on a body chart the area of pain induced by 60 seconds of suprathreshold pressure stimulation (STPS; PPT + 20%) on the right infraspinatus muscle. Skin temperature variations in the area of referred pain were recorded with an infrared thermography camera, immediately before and after the STPS. Results: Twenty healthy, pain-free individuals (10 females) participated. On Day 0, the pre-STPS temperature was higher than the post-STPS temperature on the arm (P = 0.001) and forearm (P = 0.003). On Day 1, the pre-STPS temperature was higher than the post-STPS temperature on the shoulder (P = 0.015), arm (P = 0.001), and forearm (P = 0.010). On Day 0, the temperature decrease after STPS in females was greater than in males on the forearm (P = 0.039). On Day 1, a greater temperature decrease was found amongst females compared with males at the shoulder (P = 0.018), arm (P = 0.046), and forearm (P = 0.005). Conclusions: These findings indicate that sympathetic vasomotor responses contribute to expand pressure-induced referred pain, especially among females. © The Korean Pain Society, 2022

Idioma: Inglés

DOI: 10.3344/kjp.2022.35.3.240

Año: 2022

Publicado en: Korean Journal of Pain 35, 3 (2022), 240-249
ISSN: 2005-9159

Factor impacto JCR: 2.8 (2022)

Categ. JCR: CLINICAL NEUROLOGY rank: 121 / 212 = 0.571 (2022) - Q3 - T2

Factor impacto CITESCORE: 4.0 - Medicine (Q2)

Factor impacto SCIMAGO: 0.618 - Anesthesiology and Pain Medicine (Q2)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Fisioterapia (Dpto. Fisiatría y Enfermería)