000125749 001__ 125749
000125749 005__ 20241125101129.0
000125749 0247_ $$2doi$$a10.1159/000528504
000125749 0248_ $$2sideral$$a133158
000125749 037__ $$aART-2023-133158
000125749 041__ $$aeng
000125749 100__ $$aLacort, M.
000125749 245__ $$aOptical quality variation of different intraocular lens designs in a model eye: lens placed correctly and in an upside-down position
000125749 260__ $$c2023
000125749 5060_ $$aAccess copy available to the general public$$fUnrestricted
000125749 5203_ $$aIntroduction: Intraocular lenses (IOLs) may lose their optical quality if they are not correctly placed inside the capsular bag once implanted. One possible malpositioning of the IOL could be the implantation in an upside-down position. In this work, three aspheric IOLs with different spherical aberration (SA) have been designed and numerically tested to analyse the optical quality variation with the IOL flip, and misalignments, using a theoretical model eye. Methods: Using the commercial optical design software OSLO, the effect of decentration and tilt was evaluated by numerical ray tracing in two conditions: IOL in their designed position and flipped. The Atchison theoretical model eye used. Seven IOL designs of +27.00 diopters were used: a lens with negative SA to correct the corneal SA, a lens to partially correct the corneal SA and a lens to not add any SA to the cornea (aberration-free IOL). These lenses were designed with the aspherical surface located on the anterior and posterior IOL surface. A lens with no aspherical surfaces was also included. For the optical quality analysis, the Modulation Transfer Function (MTF) and Zernike wavefront aberration coefficients of defocus, astigmatism and primary coma were used. Results: Off-centering and tilting the IOL reduced overall MTF values, and increased wavefront aberration errors. With the IOL correctly positioned within the capsular bag, an aberration-free IOL is the best choice for maintaining optical quality. When the IOL is flipped inside the capsular bag the optical quality changes, with the aberration-free IOL and the IOL without aspheric surfaces providing the worst results. With the lens in an upside-down position, an IOL design to partially correct corneal SA shows the best optical quality results in decentration and tilt. Conclusion: The aberration-free IOL is the best choice when minimal postoperative errors of decentration or tilt are predicted. With IOL flip, the negative SA lens design is the best choice, regarding the root mean square wavefront aberrations. However, in a proper IOL implantation, the IOL designed to partially compensate the corneal SA including asphericity on its posterior surface is the better possible option, even in the presence of decentration or tilt.
000125749 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/E44-20R$$9info:eu-repo/grantAgreement/ES/DGA-FSE/E24-20R$$9info:eu-repo/grantAgreement/ES/MICINN/PID2020-113822RB-C21$$9info:eu-repo/grantAgreement/ES/MICIU/PID2020-114311RA-I00
000125749 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000125749 590__ $$a2.0$$b2023
000125749 592__ $$a0.838$$b2023
000125749 591__ $$aOPHTHALMOLOGY$$b39 / 95 = 0.411$$c2023$$dQ2$$eT2
000125749 593__ $$aMedicine (miscellaneous)$$c2023$$dQ2
000125749 593__ $$aSensory Systems$$c2023$$dQ2
000125749 593__ $$aOphthalmology$$c2023$$dQ2
000125749 593__ $$aCellular and Molecular Neuroscience$$c2023$$dQ3
000125749 594__ $$a3.8$$b2023
000125749 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000125749 700__ $$aPérez-Gracia, J.
000125749 700__ $$0(orcid)0000-0002-1124-0363$$aAres, J.$$uUniversidad de Zaragoza
000125749 700__ $$0(orcid)0000-0002-3979-4528$$aRemón, L.$$uUniversidad de Zaragoza
000125749 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000125749 773__ $$g66, 1 (2023), 750–759$$pOphthalmic res.$$tOPHTHALMIC RESEARCH$$x0030-3747
000125749 8564_ $$s1255311$$uhttps://zaguan.unizar.es/record/125749/files/texto_completo.pdf$$yVersión publicada
000125749 8564_ $$s2222679$$uhttps://zaguan.unizar.es/record/125749/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000125749 909CO $$ooai:zaguan.unizar.es:125749$$particulos$$pdriver
000125749 951__ $$a2024-11-22-11:58:31
000125749 980__ $$aARTICLE