000125843 001__ 125843
000125843 005__ 20240731103403.0
000125843 0247_ $$2doi$$a10.3390/diagnostics13061101
000125843 0248_ $$2sideral$$a133374
000125843 037__ $$aART-2023-133374
000125843 041__ $$aeng
000125843 100__ $$aGonzález, Jesús
000125843 245__ $$aImpact of suspected preterm labor during pregnancy on cardiometabolic profile and neurodevelopment during childhood: a prospective cohort study protocol
000125843 260__ $$c2023
000125843 5060_ $$aAccess copy available to the general public$$fUnrestricted
000125843 5203_ $$aIntroduction: Suspected preterm labor (SPL), defined as the presence of regular and painful uterine contractions and cervical shortening, represents a prenatal insult with potential long-term consequences. However, despite recent evidence demonstrating suboptimal neurodevelopment at 2 years in this population, it remains underestimated as a significant risk factor for neurodevelopmental disorders or other chronic diseases. The aim of this study is to assess the impact of suspected preterm labor during pregnancy on cardiometabolic profile and neurodevelopment during childhood (6–8 years). Methods and analysis: Prospective cohort study including children whose mothers suffered suspected preterm labour during pregnancy and paired controls. Neurodevelopmental, cardiovascular, and metabolic assessments will be performed at 6–8 years of age. A trained psychologist will carry out the neurodevelopment assessment including intelligence, visual perception, and behavioral assessment. Body composition and physical fitness assessment will be performed by one trained pediatrician and nurse. Finally, cardiovascular evaluation, including echocardiography and blood pressure, will be performed by two pediatric cardiologists. Data regarding perinatal and postnatal characteristics, diet, lifestyle, and weekly screen time of the child will be obtained from medical history and direct interviews with families. Primary outcome measures will include body mass index and adiposity, percentage of fat mass and total and regional lean mass, bone mineral content and density, cardiorespiratory resistance, isometric muscle strength, dynamic lower body strength, systolic and diastolic blood pressure, left ventricle (LV) systolic and diastolic function, general intelligence index, visuospatial working memory span, oculomotor control test, index of emotional, and behavioral problems.
000125843 536__ $$9info:eu-repo/grantAgreement/ES/DGA-IACS-CEICA/P119-392$$9info:eu-repo/grantAgreement/ES/ISCIII/CM20-00171$$9info:eu-repo/grantAgreement/ES/ISCIII/JR19-00006$$9info:eu-repo/grantAgreement/ES/ISCIII/PI20-00741$$9info:eu-repo/grantAgreement/ES/ISCIII-RICORDS/RD21-0012-0012
000125843 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000125843 590__ $$a3.0$$b2023
000125843 592__ $$a0.667$$b2023
000125843 591__ $$aMEDICINE, GENERAL & INTERNAL$$b58 / 325 = 0.178$$c2023$$dQ1$$eT1
000125843 593__ $$aClinical Biochemistry$$c2023$$dQ2
000125843 594__ $$a4.7$$b2023
000125843 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000125843 700__ $$aVilella, Marina
000125843 700__ $$aRuiz, Sonia
000125843 700__ $$0(orcid)0000-0002-2219-3646$$aIglesia, Iris
000125843 700__ $$aClavero-Adell, Marcos
000125843 700__ $$aAyerza-Casas, Ariadna
000125843 700__ $$0(orcid)0000-0001-8500-1667$$aMatute-Llorente, Angel$$uUniversidad de Zaragoza
000125843 700__ $$0(orcid)0000-0002-8476-9161$$aOros, Daniel$$uUniversidad de Zaragoza
000125843 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, Jose Antonio$$uUniversidad de Zaragoza
000125843 700__ $$0(orcid)0000-0002-1777-0349$$aPueyo, Victoria$$uUniversidad de Zaragoza
000125843 700__ $$0(orcid)0000-0002-7985-9912$$aRodriguez, Gerardo$$uUniversidad de Zaragoza
000125843 700__ $$0(orcid)0000-0001-6795-0367$$aPaules, Cristina$$uUniversidad de Zaragoza
000125843 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000125843 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología
000125843 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000125843 7102_ $$11011$$2670$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Pediatría
000125843 773__ $$g13, 6 (2023), 1101 [13 pp.]$$tDiagnostics$$x2075-4418
000125843 8564_ $$s458890$$uhttps://zaguan.unizar.es/record/125843/files/texto_completo.pdf$$yVersión publicada
000125843 8564_ $$s2860212$$uhttps://zaguan.unizar.es/record/125843/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000125843 909CO $$ooai:zaguan.unizar.es:125843$$particulos$$pdriver
000125843 951__ $$a2024-07-31-10:00:07
000125843 980__ $$aARTICLE