125989 20241125101141.0 doi 10.3389/fpsyg.2023.1008891 sideral 133532 ART-2023-133532 eng Garcia-Toro, Mauro Mindfulness skills and experiential avoidance as therapeutic mechanisms for treatment-resistant depression through mindfulness-based cognitive therapy and lifestyle modification 2023 Access copy available to the general public Unrestricted Background/objective: The COVID-19 pandemic and consequent physical distancing has made it difficult to provide care for those with Treatment-Resistant Depression (TRD). As a secondary analysis of a clinical trial, the aim of this study was to explore potential mechanisms through which three online-delivered approaches, added to treatment as usual, improve depressive symptoms in TRD patients. Methods: The three approaches included (a) Minimal Lifestyle Intervention (MLI), (b) Mindfulness-Based Cognitive Therapy (MBCT), and (c) Lifestyle Modification Program (LMP). Sixty-six participants with TRD completed assessments pre-post intervention (mindfulness skills [FFMQ]; self-compassion [SCS]; and experiential avoidance [AAQ-II]) and pre-intervention to follow-up (depressive symptoms [BDI-II]). Data were analyzed using within-subjects regression models to test mediation. Results: Mindfulness skills mediated the effect of MBCT on depressive symptoms (ab = −4.69, 95% CI = −12.93 to−0.32), whereas the lack of experiential avoidance mediated the effect of LMP on depressive symptoms (ab = −3.22, 95% CI = −7.03 to−0.14). Conclusion: Strengthening mindfulness skills and decreasing experiential avoidance may promote recovery in patients with TRD, MBCT, and LMP have demonstrated that they may help increase mindfulness skills and decrease experiential avoidance, respectively. Future work will need to unpick the components of these interventions to help isolate active ingredients and increase optimization. info:eu-repo/grantAgreement/ES/DGA-FEDER/Another way to make Europe info:eu-repo/grantAgreement/ES/MCIU/RTI2018-093590-B-I00 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.6 2023 PSYCHOLOGY, MULTIDISCIPLINARY 56 / 219 = 0.256 2023 Q2 T1 0.8 2023 Psychology (miscellaneous) 2023 Q2 5.3 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Aguilar-Latorre, Alejandra Universidad de Zaragoza (orcid)0000-0003-2683-7346 Garcia, Aurora Navarro-Guzmán, Capilla Gervilla, Elena Seguí, Andrea Gazquez, Francisco Marino, Jose Antonio Gomez-Juanes, Rocío Serrano-Ripoll, María J. Oliván-Blázquez, Bárbara Universidad de Zaragoza (orcid)0000-0001-6565-9699 Garcia-Campayo, Javier Universidad de Zaragoza (orcid)0000-0002-3797-4218 Maloney, Shannon Montero-Marin, Jesús 4009 740 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Social 1007 745 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Psiquiatría 4009 735 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicolog.Evolut.Educac 14 (2023), [9 pp.] Front. psychol. Frontiers in Psychology 1664-1078 330309 http://zaguan.unizar.es/record/125989/files/texto_completo.pdf Versión publicada 2244189 http://zaguan.unizar.es/record/125989/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:125989 articulos driver 2024-11-22-12:02:41 ARTICLE