126024 20241125101152.0 doi 10.1038/s41598-023-33456-w sideral 133518 ART-2023-133518 eng Muñoz-Cabrejas, Ainara Association of beverage consumption with subclinical atherosclerosis in a Spanish working population 2023 Access copy available to the general public Unrestricted Beverages play a substantial role meeting water, calorie, and nutrient requirements; however, they are presented as being major contributors to the current obesity epidemic. Although, the relationship between beverage consumption and metabolic risk factors for cardiovascular disease (CVD) in adults has been frequently studied, its association with subclinical atherosclerosis is of increased interest. We studied the association of beverage consumption with the presence of peripheral subclinical atherosclerosis among Spanish workers. We performed a cross-sectional study of 2089 middle-aged males, with a mean age of 50.9 (SD 3.9), and without CVD, carried out in the Aragon Workers’ Health Study (AWHS). A food frequency questionnaire was used to measure beverage consumption of low-fat milk, coffee and tea (unsweetened), whole-fat milk, sugar-sweetened beverages, bottled fruit juice, artificially-sweetened beverages and 100% fruit juice. Atherosclerotic plaques were measured by ultrasound (in carotid arteries, and in femoral arteries). Atherosclerotic plaque was defined as a focal structure protruding ≥ 0.5 mm into the lumen, or reaching a thickness ≥ 50% of the surrounding intima-media thickness. As statistical analysis, we use logistic regression models, simultaneously adjusted for all beverage groups. As results, unsweetened coffee was the beverage most associated with peripheral subclinical atherosclerosis with an odds ratio (OR) of 1.25 (1.10–1.41), and 1.23 (1.09–1.40) 100g/day] for carotid, and femoral territories respectively. Moreover, subclinical atherosclerosis was positively associated with whole-fat milk [OR 1.10 (1.02–1.18) 100 g/day] in the femoral territory. The association was protective for low-fat milk in the carotid territory [OR 0.93 (0.88–0.99) 100g/day]. There was also a protective association with bottled fruit juices in the femoral territory [0.84 (0.74–0.94) 100g/day]. Our results suggest a detrimental association with the consumption of coffee, as well as with whole-fat milk and the presence of subclinical atherosclerosis. Therefore, an element of prudence excluding water and low-fat milk, must be applied when recommending beverage consumption. info:eu-repo/grantAgreement/ES/ISCIII-FIS/PI17-01709 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI18-01929 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI19-00020 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI19-00948 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.8 2023 MULTIDISCIPLINARY SCIENCES 25 / 134 = 0.187 2023 Q1 T1 0.9 2023 Multidisciplinary 2023 Q1 7.5 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Laclaustra, Martín Universidad de Zaragoza (orcid)0000-0003-3963-0846 Guallar-Castillón, Pilar Sánchez-Recio, Raquel Universidad de Zaragoza (orcid)0000-0002-0078-0663 Jarauta, Estíbaliz Universidad de Zaragoza (orcid)0000-0001-9142-0737 Casasnovas, José Antonio Universidad de Zaragoza (orcid)0000-0002-9887-2629 Moreno-Franco, Belén Universidad de Zaragoza (orcid)0000-0003-0604-5042 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 1011 615 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Medic.Prevent.Salud Públ. 13 (2023), 6509 [8 pp.] Sci. rep. (Nat. Publ. Group) Scientific reports (Nature Publishing Group) 2045-2322 933666 http://zaguan.unizar.es/record/126024/files/texto_completo.pdf Versión publicada 2251166 http://zaguan.unizar.es/record/126024/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:126024 articulos driver 2024-11-22-12:07:20 ARTICLE