126544 20241125101145.0 doi 10.3390/jpm13050822 sideral 134002 ART-2023-134002 eng Fernández-Espinosa, Guisela (orcid)0000-0003-1234-9712 A reliable criterion for the correct delimitation of the foveal avascular zone in diabetic patients 2023 Access copy available to the general public Unrestricted Background: Manual segmentation of the Foveal Avascular Zone (FAZ) has a high level of variability. Research into retinas needs coherent segmentation sets with low variability. Methods: Retinal optical coherence tomography angiography (OCTA) images from type-1 diabetes mellitus (DM1), type-2 diabetes mellitus (DM2) and healthy patients were included. Superficial (SCP) and deep (DCP) capillary plexus FAZs were manually segmented by different observers. After comparing the results, a new criterion was established to reduce variability in the segmentations. The FAZ area and acircularity were also studied. Results: The new segmentation criterion produces smaller areas (closer to the real FAZ) with lower variability than the different criteria of the explorers in both plexuses for the three groups. This was particularly noticeable for the DM2 group with damaged retinas. The acircularity values were also slightly reduced with the final criterion in all groups. The FAZ areas with lower values showed slightly higher acircularity values. We also have a consistent and coherent set of segmentations with which to continue our research. Conclusions: Manual segmentations of FAZ are generally carried out with little attention to the consistency of the measurements. A novel criterion for segmenting the FAZ allows segmentations made by different observers to be more similar. info:eu-repo/grantAgreement/ES/FEDER/Una manera de hacer Europa info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI20-00740 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.0 2023 MEDICINE, GENERAL & INTERNAL 59 / 329 = 0.179 2023 Q1 T1 HEALTH CARE SCIENCES & SERVICES 51 / 174 = 0.293 2023 Q2 T1 0.736 2023 Medicine (miscellaneous) 2023 Q2 4.1 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Ruiz-Tabuenca, Carlos Orduna-Hospital, Elvira Universidad de Zaragoza (orcid)0000-0003-2710-1875 Pinilla, Isabel Universidad de Zaragoza (orcid)0000-0003-0349-9997 Salgado-Remacha, Francisco J. Universidad de Zaragoza (orcid)0000-0002-6048-310X 2002 385 Universidad de Zaragoza Dpto. Física Aplicada Área Física Aplicada 1013 646 Universidad de Zaragoza Dpto. Cirugía Área Oftalmología 2002 647 Universidad de Zaragoza Dpto. Física Aplicada Área Óptica 13, 5 (2023), 822 [13 pp.] J. pers. med. Journal of Personalized Medicine 2075-4426 6332078 http://zaguan.unizar.es/record/126544/files/texto_completo.pdf Versión publicada 2658172 http://zaguan.unizar.es/record/126544/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:126544 articulos driver 2024-11-22-12:04:22 ARTICLE