126552 20241125101147.0 doi 10.1177/20417314231177838 sideral 134048 ART-2023-134048 eng Lecina-Tejero, Óscar Universidad de Zaragoza The rise of mechanical metamaterials: Auxetic constructs for skin wound healing 2023 Access copy available to the general public Unrestricted Auxetic materials are known for their unique ability to expand/contract in multiple directions when stretched/compressed. In other words, they exhibit a negative Poisson’s ratio, which is usually positive for most of materials. This behavior appears in some biological tissues such as human skin, where it promotes wound healing by providing an enhanced mechanical support and facilitating cell migration. Skin tissue engineering has been a growing research topic in recent years, largely thanks to the rapid development of 3D printing techniques and technologies. The combination of computational studies with rapid manufacturing and tailored designs presents a huge potential for the future of personalized medicine. Overall, this review article provides a comprehensive overview of the current state of research on auxetic constructs for skin healing applications, highlighting the potential of auxetics as a promising treatment option for skin wounds. The article also identifies gaps in the current knowledge and suggests areas for future research. In particular, we discuss the designs, materials, manufacturing techniques, and also the computational and experimental studies on this topic. info:eu-repo/grantAgreement/ES/DGA/LMP 176-21 info:eu-repo/grantAgreement/ES/MICINN/RYC2021-033490-I info:eu-repo/grantAgreement/ES/MINECO/PID2020-113819RB-I00 info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 6.7 2023 CELL & TISSUE ENGINEERING 4 / 31 = 0.129 2023 Q1 T1 1.262 2023 Biomaterials 2023 Q1 Medicine (miscellaneous) 2023 Q1 Biomedical Engineering 2023 Q1 11.6 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Pérez, María Ángeles Universidad de Zaragoza (orcid)0000-0002-2901-4188 García-Gareta, Elena Universidad de Zaragoza (orcid)0000-0001-7062-9099 Borau, Carlos Universidad de Zaragoza (orcid)0000-0002-3784-1140 5004 605 Universidad de Zaragoza Dpto. Ingeniería Mecánica Área Mec.Med.Cont. y Teor.Est. 5001 065 Universidad de Zaragoza Dpto. Ciencia Tecnol.Mater.Fl. Área Cienc.Mater. Ingen.Metal. 14 (2023), [16 pp.] Journal of Tissue Engineering Journal of Tissue Engineering 2041-7314 2237947 http://zaguan.unizar.es/record/126552/files/texto_completo.pdf Versión publicada 2541886 http://zaguan.unizar.es/record/126552/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:126552 articulos driver 2024-11-22-12:04:48 ARTICLE