000126584 001__ 126584
000126584 005__ 20241125101133.0
000126584 0247_ $$2doi$$a10.3390/ijms24108573
000126584 0248_ $$2sideral$$a134093
000126584 037__ $$aART-2023-134093
000126584 041__ $$aeng
000126584 100__ $$aVázquez-Morón, Sonia
000126584 245__ $$aEnhancing SARS-CoV-2 Surveillance through Regular Genomic Sequencing in Spain: The RELECOV Network
000126584 260__ $$c2023
000126584 5060_ $$aAccess copy available to the general public$$fUnrestricted
000126584 5203_ $$aMillions of SARS-CoV-2 whole genome sequences have been generated to date. However, good quality data and adequate surveillance systems are required to contribute to meaningful surveillance in public health. In this context, the network of Spanish laboratories for coronavirus (RELECOV) was created with the main goal of promoting actions to speed up the detection, analyses, and evaluation of SARS-CoV-2 at a national level, partially structured and financed by an ECDC-HERA-Incubator action (ECDC/GRANT/2021/024). A SARS-CoV-2 sequencing quality control assessment (QCA) was developed to evaluate the network’s technical capacity. QCA full panel results showed a lower hit rate for lineage assignment compared to that obtained for variants. Genomic data comprising 48,578 viral genomes were studied and evaluated to monitor SARS-CoV-2. The developed network actions showed a 36% increase in sharing viral sequences. In addition, analysis of lineage/sublineage-defining mutations to track the virus showed characteristic mutation profiles for the Delta and Omicron variants. Further, phylogenetic analyses strongly correlated with different variant clusters, obtaining a robust reference tree. The RELECOV network has made it possible to improve and enhance the genomic surveillance of SARS-CoV-2 in Spain. It has provided and evaluated genomic tools for viral genome monitoring and characterization that make it possible to increase knowledge efficiently and quickly, promoting the genomic surveillance of SARS-CoV-2 in Spain.
000126584 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/COV20-00679
000126584 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000126584 590__ $$a4.9$$b2023
000126584 592__ $$a1.179$$b2023
000126584 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b66 / 313 = 0.211$$c2023$$dQ1$$eT1
000126584 593__ $$aMedicine (miscellaneous)$$c2023$$dQ1
000126584 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b68 / 231 = 0.294$$c2023$$dQ2$$eT1
000126584 593__ $$aPhysical and Theoretical Chemistry$$c2023$$dQ1
000126584 593__ $$aComputer Science Applications$$c2023$$dQ1
000126584 593__ $$aInorganic Chemistry$$c2023$$dQ1
000126584 593__ $$aSpectroscopy$$c2023$$dQ1
000126584 593__ $$aOrganic Chemistry$$c2023$$dQ1
000126584 593__ $$aMolecular Biology$$c2023$$dQ2
000126584 593__ $$aCatalysis$$c2023$$dQ2
000126584 594__ $$a8.1$$b2023
000126584 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000126584 700__ $$aIglesias-Caballero, María
000126584 700__ $$aLepe, José
000126584 700__ $$aGarcia, Federico
000126584 700__ $$aMelón, Santiago
000126584 700__ $$aMarimon, José
000126584 700__ $$aGarcía de Viedma, Darío
000126584 700__ $$aFolgueira, Maria
000126584 700__ $$aGalán, Juan
000126584 700__ $$aLópez-Causapé, Carla
000126584 700__ $$0(orcid)0000-0001-5134-1006$$aBenito-Ruesca, Rafael$$uUniversidad de Zaragoza
000126584 700__ $$aAlcoba-Florez, Julia
000126584 700__ $$aGonzalez Candelas, Fernando
000126584 700__ $$aToro, María
000126584 700__ $$aFajardo, Miguel
000126584 700__ $$aEzpeleta, Carmen
000126584 700__ $$aLázaro, Fernando
000126584 700__ $$aPérez Castro, Sonia
000126584 700__ $$aCuesta, Isabel
000126584 700__ $$aZaballos, Angel
000126584 700__ $$aPozo, Francisco
000126584 700__ $$aCasas, Inmaculada
000126584 700__ $$aon behalf of RELECOV Network Members
000126584 7102_ $$11011$$2630$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Microbiología
000126584 773__ $$g24, 10 (2023), 8573 [17 pp.]$$pInt. j. mol. sci.$$tInternational Journal of Molecular Sciences$$x1661-6596
000126584 8564_ $$s1987887$$uhttps://zaguan.unizar.es/record/126584/files/texto_completo.pdf$$yVersión publicada
000126584 8564_ $$s2791311$$uhttps://zaguan.unizar.es/record/126584/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000126584 909CO $$ooai:zaguan.unizar.es:126584$$particulos$$pdriver
000126584 951__ $$a2024-11-22-11:59:30
000126584 980__ $$aARTICLE