126776 20241125101139.0 doi 10.1016/j.critrevonc.2023.104020 sideral 134179 ART-2023-134179 eng Campa, Daniele The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years’ experience of association studies to understand the genetic architecture of pancreatic cancer 2023 Access copy available to the general public Unrestricted Pancreatic cancer has an incidence that almost matches its mortality. Only a small number of risk factors and 33 susceptibility loci have been identified. so Moreover, the relative rarity of pancreatic cancer poses significant hurdles for research aimed at increasing our knowledge of the genetic mechanisms contributing to the disease. Additionally, the inability to adequately power research questions prevents small monocentric studies from being successful. Several consortia have been established to pursue a better understanding of the genetic architecture of pancreatic cancers. The Pancreatic disease research (PANDoRA) consortium is the largest in Europe. PANDoRA is spread across 12 European countries, Brazil and Japan, bringing together 29 basic and clinical research groups. In the last ten years, PANDoRA has contributed to the discovery of 25 susceptibility loci, a feat that will be instrumental in stratifying the population by risk and optimizing preventive strategies. info:eu-repo/grantAgreement/EUR/COST-Action/CA21116-TRANSPAN info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 5.5 2023 ONCOLOGY 59 / 322 = 0.183 2023 Q1 T1 HEMATOLOGY 15 / 97 = 0.155 2023 Q1 T1 1.572 2023 Geriatrics and Gerontology 2023 Q1 Oncology 2023 Q1 Hematology 2023 Q1 11.0 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Gentiluomo, Manuel Stein, Angelika Aoki, Mateus Nóbrega Oliverius, Martin Vodicková, Ludmila Jamroziak, Krzysztof Theodoropoulos, George Pasquali, Claudio Greenhalf, William Arcidiacono, Paolo Giorgio Uzunoglu, Faik Pezzilli, Raffaele Luchini, Claudio Puzzono, Marta Loos, Martin Giaccherini, Matteo Katzke, Verena Mambrini, Andrea Kiudeliene, Edita Federico, Kauffmann Emanuele Johansen, Julia Hussein, Tamás Mohelnikova-Duchonova, Beatrice van Eijck, Casper H.J. Brenner, Hermann Farinella, Riccardo Pérez, Juan Sainz Lovecek, Martin Büchler, Markus W. Hlavac, Viktor Izbicki, Jakob R. Hackert, Thilo Chammas, Roger Zerbi, Alessandro Lawlor, Rita Felici, Alessio Götz, Mara Capurso, Gabriele Ginocchi, Laura Gazouli, Maria Kupcinskas, Juozas Cavestro, Giulia Martina Vodicka, Pavel Moz, Stefania Neoptolemos, John P. Kunovsky, Lumir Bojesen, Stig E. Carrara, Silvia Gioffreda, Domenica Morkunas, Egidijus Abian, Olga Universidad de Zaragoza (orcid)0000-0001-5664-1729 Bunduc, Stefania Basso, Daniela Boggi, Ugo Wlodarczyk, Barbara Szentesi, Andrea Vanella, Giuseppe Chen, Inna Bijlsma, Maarten F. Kiudelis, Vytautas Landi, Stefano Schöttker, Ben Corradi, Chiara Giese, Nathalia Kaaks, Rudolf Peduzzi, Giulia Hegyi, Péter Morelli, Luca Furbetta, Niccolò Soucek, Pavel Latiano, Anna Talar-Wojnarowska, Renata Lindgaard, Sidsel C. Dijk, Frederike Milanetto, Anna Caterina Tavano, Francesca Cervena, Klara Eross, Bálint Testoni, Sabrina G. Verhagen-Oldenampsen, Judith H.E. Malecka-Wojciesko, Ewa Costello, Eithne Salvia, Roberto Maiello, Evaristo Ermini, Stefano Sperti, Cosimo Holleczek, Bernd Perri, Francesco Skieceviciene, Jurgita Archibugi, Livia Lucchesi, Maurizio Rizzato, Cosmeri Canzian, Federico 1002 060 Universidad de Zaragoza Dpto. Bioq.Biolog.Mol. Celular Área Bioquímica y Biolog.Mole. 186 (2023), 104020 [13 pp.] Crit. rev. oncol./hematol. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 1040-8428 2592171 http://zaguan.unizar.es/record/126776/files/texto_completo.pdf Versión publicada 2655827 http://zaguan.unizar.es/record/126776/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:126776 articulos driver 2024-11-22-12:02:03 ARTICLE