126905 20240319081011.0 doi 10.1111/tbed.14649 sideral 129773 ART-2022-129773 eng Varela-Castro, L. Beyond tuberculosis: Diversity and implications of non-tuberculous mycobacteria at the wildlife–livestock interface 2022 Access copy available to the general public Unrestricted Non-tuberculous mycobacteria (NTM) circulate between the environment, animals and humans entailing a double concern: their ability to interfere with tuberculosis diagnosis and their potential to cause infections in their hosts. However, published records on NTM infections in animals are still scarce. The aims of the present study were to describe the diversity of NTM circulating among wild and domestic species from Spain and to analyze their implications as potential pathogenic microorganisms or as sources of interferences in the diagnosis of bovine tuberculosis. Overall, 293 NTM isolates of 277 animals were obtained from tissue samples collected between 2012 and 2019, and analyzed through a multigene approach for mycobacteria identification. Thirty-one species were identified, being Mycobacterium avium subsp. avium (Maa) and M. avium subsp. hominissuis (Mah), but also M. bouchedurhonense, M. nonchromogenicum and M. lentiflavum, the most abundant ones. Maa and M. lentiflavum were isolated in several animals showing tuberculosis-like lesions. Maa, Mah and M. nonchromogenicum were recovered from many cattle that had reacted to the tuberculin skin test. Other NTM were also associated to these phenomena. These four mycobacterial species were geographically associated between wild boar and other hosts. The findings of the present study suggest that a high diversity of NTM circulates among wildlife and livestock. Wild boar and M. avium seem to play a relevant role in this epidemiological scenario. info:eu-repo/grantAgreement/ES/AEI/PID2019-105155RB-C33 info:eu-repo/grantAgreement/ES/INIA/CPD-2016-0006 info:eu-repo/grantAgreement/ES/Interreg POCTEFA 357-19-INNOTUB AND VEPIFAUS info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 4.3 2022 VETERINARY SCIENCES 7 / 144 = 0.049 2022 Q1 T1 INFECTIOUS DISEASES 42 / 96 = 0.438 2022 Q2 T2 0.99 2022 Medicine (miscellaneous) 2022 Q1 Veterinary (miscellaneous) 2022 Q1 Immunology and Microbiology (miscellaneous) 2022 Q2 7.4 2022 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Barral, M. Arnal, M. C. Universidad de Zaragoza (orcid)0000-0002-6770-3400 Fernández de Luco, D. Universidad de Zaragoza (orcid)0000-0003-3289-4267 Gortázar, C. Garrido, J. M. Sevilla, I. A. 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 69, 5 (2022), e2978-e2993 Transboundary and Emerging Diseases Transboundary and Emerging Diseases 1865-1674 3369024 http://zaguan.unizar.es/record/126905/files/texto_completo.pdf Postprint 1404535 http://zaguan.unizar.es/record/126905/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:126905 articulos driver 2024-03-18-15:10:54 ARTICLE