000126961 001__ 126961
000126961 005__ 20240731103344.0
000126961 0247_ $$2doi$$a10.1111/jbg.12811
000126961 0248_ $$2sideral$$a134356
000126961 037__ $$aART-2023-134356
000126961 041__ $$aeng
000126961 100__ $$aPerdomo-González, Davinia I.
000126961 245__ $$aQuantitative analysis of parent-of-origin effect in reproductive and morphological selection criteria in the Pura Raza Española horse
000126961 260__ $$c2023
000126961 5060_ $$aAccess copy available to the general public$$fUnrestricted
000126961 5203_ $$aIt is generally assumed that parents make a genetically equal contribution to their offspring, but this assumption might not always hold. This is because the expression of a gene can be blocked by methylation during gametogenesis, and the degree of methylation can depend on the origin of the parental gene (imprinting) or by preferential management associated with genetic merit. The first consequences of this for quantitative genetics is that the mean phenotypes of reciprocal heterozygotes need no longer be the same, as would be expected according to Mendelian heritage. We analysed three mare reproductive traits (reproductive efficiency, age at first foaling and foaling number) and three morphological traits (height at withers, thoracic circumference, and scapula‐ischial length) in the Pura Raza Española (PRE) horse population, which possesses a deep and reliable pedigree, making it a perfect breed for analysing the quantitative effect of parent‐of‐origin. The number of animals analysed ranged from 44,038 to 144,191, all of them with both parents known. The model comparison between a model without parent‐of‐origin effects and three different models with parent‐of‐origin effects revealed that both maternal and paternal gametic effects influence all the analysed traits. The maternal gametic effect had a higher influence on most traits, accounting for between 3% and 11% of the total phenotypic variance, while the paternal gametic effect accounted for a higher proportion of variance in one trait, age at first foaling (4%). As expected, the Pearson's correlations between additive breeding values of models that consider parent‐of‐origin and that do not consider parent‐of‐origin were very high; however, the percentage of coincident animals slightly decreases when comparing animals with the highest estimated breeding values. Ultimately, this work demonstrates that parent‐of‐origin effects exist in horse gene transmission from a quantitative point of view. Additionally, including an estimate of the parent‐of‐origin effect within the PRE horse breeding program could be a great tool for a better parent's selection and that could be of interest for breeders, as this value will determine whether the animals acquire genetic categories and are much more highly valued.
000126961 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/AGL2017-84217-P
000126961 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000126961 590__ $$a1.9$$b2023
000126961 592__ $$a0.703$$b2023
000126961 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b21 / 80 = 0.262$$c2023$$dQ2$$eT1
000126961 593__ $$aAnimal Science and Zoology$$c2023$$dQ1
000126961 593__ $$aFood Animals$$c2023$$dQ1
000126961 593__ $$aMedicine (miscellaneous)$$c2023$$dQ2
000126961 594__ $$a5.2$$b2023
000126961 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000126961 700__ $$0(orcid)0000-0001-6256-5478$$aVarona, Luis$$uUniversidad de Zaragoza
000126961 700__ $$aMolina, Antonio
000126961 700__ $$aLaseca, Nora
000126961 700__ $$aValera, Mercedes
000126961 7102_ $$11001$$2420$$aUniversidad de Zaragoza$$bDpto. Anatom.,Embri.Genét.Ani.$$cÁrea Genética
000126961 773__ $$g140, 6 (2023), 596-606$$pJ. anim. breed. genet.$$tJOURNAL OF ANIMAL BREEDING AND GENETICS$$x0931-2668
000126961 8564_ $$s898289$$uhttps://zaguan.unizar.es/record/126961/files/texto_completo.pdf$$yVersión publicada
000126961 8564_ $$s2385870$$uhttps://zaguan.unizar.es/record/126961/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000126961 909CO $$ooai:zaguan.unizar.es:126961$$particulos$$pdriver
000126961 951__ $$a2024-07-31-09:51:24
000126961 980__ $$aARTICLE