000127684 001__ 127684
000127684 005__ 20241125101157.0
000127684 0247_ $$2doi$$a10.3390/ani13162565
000127684 0248_ $$2sideral$$a134770
000127684 037__ $$aART-2023-134770
000127684 041__ $$aeng
000127684 100__ $$aContreras-Solís, Ignacio
000127684 245__ $$aThe effect of by-pass linseed oil supplementation on the maternal antioxidant system during the embryo-maternal recognition period in ewes
000127684 260__ $$c2023
000127684 5060_ $$aAccess copy available to the general public$$fUnrestricted
000127684 5203_ $$aThis study analyzed the effects of dietary supplementation with by-pass linseed oil (LO; rich in α-linolenic acid) on maternal antioxidant systems at Days 14 and 16 of pregnancy in Sarda ewes. This trial used sixteen dry ewes. Eight ewes (CT group) were fed with a control diet without LO, and eight ewes (LO group) were fed with a diet supplemented with LO (10.8 g of α-linolenic acid/ewe/day). Both diets had similar crude protein and energy levels. The experiment included 10 days of an adaptation period and 31 days of a supplementation period. This supplementation period was divided into Period −2 (from Day −15 to −8), Period −1 (from Day −7 to −1; before synchronized mating period/Day 0), Period +1 (from Day +1 to + 7 after mating), and Period +2 (from Day +8 to +15 after mating). Estrous synchronization was induced in all the ewes using an intravaginal sponge (45 mg fluorgestone acetate) for 14 days and equine chorionic gonadotropin (350 UI/ewe) at the end of the treatment. On Days 14 (CT, N = 4; LO, N = 4) and 16 (CT, N = 4; LO, N = 4) after mating, the ewes were slaughtered. Samples of plasma, uterine, and luteal tissues were collected. Thiols, total antioxidant activity (TEAC), superoxide dismutase (SOD) activity, and malondialdehyde (MDA) content were measured. On Day 16, thiol and TEAC in luteal tissues were higher in the LO group when compared with the control one (p < 0.05). Moreover, TEAC was higher for the LO group in uterine tissues on Days 14 and 16 (p < 0.05). SOD activity was higher in the LO group in luteal and uterine tissues on Day 14 and Day 16, respectively (p < 0.001). On Day 16, uterine MDA content was lower for the LO group (p < 0.001). No differences were found between groups at the plasmatic level. However, the by-pass LO supplementation enhanced the analyzed antioxidant parameters in luteal and uterine tissues. In conclusion, these results demonstrate that by-pass LO supplementation exerted a positive effect on antioxidative defenses on maternal structures during the embryo-maternal recognition period in ewes. Thus, this could contribute to improving the maternal environment during the embryo-maternal recognition period in mammals.
000127684 536__ $$9info:eu-repo/grantAgreement/EC/H2020/832326/EU/Effect of polyinsatured fatty acids omega-3 (PUFAS n-3) supplementation during early embryo development on embryo viability in (mammals) sheep./NUTREPHEALTH$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 832326-NUTREPHEALTH
000127684 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000127684 590__ $$a2.7$$b2023
000127684 592__ $$a0.698$$b2023
000127684 591__ $$aVETERINARY SCIENCES$$b16 / 167 = 0.096$$c2023$$dQ1$$eT1
000127684 593__ $$aVeterinary (miscellaneous)$$c2023$$dQ1
000127684 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b10 / 80 = 0.125$$c2023$$dQ1$$eT1
000127684 593__ $$aAnimal Science and Zoology$$c2023$$dQ1
000127684 594__ $$a4.9$$b2023
000127684 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000127684 700__ $$aPasciu, Valeria
000127684 700__ $$aPorcu, Cristian
000127684 700__ $$aSotgiu, Francesca D.
000127684 700__ $$aTodorova, Neda
000127684 700__ $$aBaralla, Elena
000127684 700__ $$aMara, Laura
000127684 700__ $$aGallus, Marilia
000127684 700__ $$aCabiddu, Andrea
000127684 700__ $$aDattena, Maria
000127684 700__ $$0(orcid)0000-0003-2827-3054$$aAbecia, José Alfonso$$uUniversidad de Zaragoza
000127684 700__ $$aBerlinguer, Fiammetta
000127684 7102_ $$12008$$2700$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Producción Animal
000127684 773__ $$g13, 16 (2023), 2565 [14 pp.]$$pAnimals (Basel)$$tAnimals$$x2076-2615
000127684 8564_ $$s1643584$$uhttps://zaguan.unizar.es/record/127684/files/texto_completo.pdf$$yVersión publicada
000127684 8564_ $$s2771050$$uhttps://zaguan.unizar.es/record/127684/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000127684 909CO $$ooai:zaguan.unizar.es:127684$$particulos$$pdriver
000127684 951__ $$a2024-11-22-12:09:45
000127684 980__ $$aARTICLE