127791 20241125101144.0 doi 10.3390/molecules28155861 sideral 134946 ART-2023-134946 eng Sánchez-Hernández, Eva Helichrysum stoechas (L.) Moench Inflorescence Extract for Tomato Disease Management 2023 Access copy available to the general public Unrestricted Helichrysum stoechas is a singular halophyte that has been shown to have anti-inflammatory, antioxidant, and allelopathic properties. In the work presented herein, we have characterized its inflorescences hydromethanolic extract and assessed its antifungal activity for the pre- and postharvest management of tomato crop diseases. Gas chromatography–mass spectrometry characterization of the extract showed that 4-ethenyl-1,3-benzenediol, 2,3-dihydro-benzofuran, quinic acid, 3,5-dihydroxy-6,7,8-trimethoxy-2-phenyl-4H-1-benzopyran-4-one, 1,6-anhydro-β-D-glucopyranose, catechol, scopoletin, and maltol were the main constituents. The co-occurrence of pyranones, benzenediols, and quinic acids as phytoconstituents of H. stoechas extract resulted in promising in vitro minimum inhibitory concentrations of 500, 375, 500, 187.5, 187.5, and 375 μg·mL−1 against mycelia of Alternaria alternata, Colletotrichum coccodes, Fusarium oxysporum f. sp. lycopersici, Rhizoctonia solani, Sclerotinia sclerotiorum, and Verticillium dahliae, respectively. Further, to assess the potential of H. stoechas inflorescence extract for postharvest tomato crop protection, ex situ tests were conducted against C. coccodes, obtaining high protection at a dose of 750 μg·mL−1. Taking into consideration that the demonstrated activity is among the highest reported to date for plant extracts and comparable to that of the synthetic fungicides tested as positive controls, H. stoechas inflorescence extract may be put forward as a promising biorational and may deserve further testing in field-scale studies. info:eu-repo/grantAgreement/ES/AEI/PID2020-116055RB-C22 info:eu-repo/grantAgreement/ES/DGA/A11-20R info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 4.2 2023 CHEMISTRY, MULTIDISCIPLINARY 77 / 231 = 0.333 2023 Q2 T2 BIOCHEMISTRY & MOLECULAR BIOLOGY 88 / 313 = 0.281 2023 Q2 T1 0.744 2023 Analytical Chemistry 2023 Q1 Pharmaceutical Science 2023 Q1 Chemistry (miscellaneous) 2023 Q1 Organic Chemistry 2023 Q2 Physical and Theoretical Chemistry 2023 Q2 Drug Discovery 2023 Q2 Medicine (miscellaneous) 2023 Q2 Molecular Medicine 2023 Q3 7.4 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Álvarez-Martínez, Javier González-García, Vicente Universidad de Zaragoza (orcid)0000-0002-2535-6914 Casanova-Gascón, José Universidad de Zaragoza (orcid)0000-0003-3009-0935 Martín-Gil, Jesús Martín-Ramos, Pablo 5011 705 Universidad de Zaragoza Dpto. CC.Agrar.y Medio Natural Área Producción Vegetal 5011 063 Universidad de Zaragoza Dpto. CC.Agrar.y Medio Natural Área Botánica 28, 15 (2023), 5861 [17 pp.] Molecules (Basel, Online) Molecules 1420-3049 1559943 http://zaguan.unizar.es/record/127791/files/texto_completo.pdf Versión publicada 2774936 http://zaguan.unizar.es/record/127791/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:127791 articulos driver 2024-11-22-12:03:44 ARTICLE