000127804 001__ 127804
000127804 005__ 20241125101146.0
000127804 0247_ $$2doi$$a10.3390/nu15173775
000127804 0248_ $$2sideral$$a134956
000127804 037__ $$aART-2023-134956
000127804 041__ $$aeng
000127804 100__ $$aKintossou, Ambroise Kouame
000127804 245__ $$aEarly Life Nutrition Factors and Risk of Acute Leukemia in Children: Systematic Review and Meta-Analysis
000127804 260__ $$c2023
000127804 5060_ $$aAccess copy available to the general public$$fUnrestricted
000127804 5203_ $$aAcute leukemia commonly occurs in young children with peak incidence at the age of 2–5 years. However, the etiology is still unclear and many preventable risk factors still deserve to be reviewed. The focus of this systematic review and meta-analysis is to summarize the evidence concerning early life nourishment (breastfeeding, early life diet), neonatal vitamin K administration and the risk of acute leukemia. All epidemiological studies published up to June 2023 and assessing diet-related risk factors for childhood acute leukemia were identified in two electronic databases (PubMed and Web of Science), with no limits on publication year or language. A total of 38 studies (37 case–control studies and 1 study with pooled analysis) were included. The published risk estimates were combined into a meta-analysis using the Generic Inverse Variance method. The current evidence shows that breastfeeding (yes vs. no) has a protective effect against acute lymphoblastic leukemia (odds ratio = 0.85; 95% CI, 0.76–0.94). Evidence related to the role of other studied factors (foods and supplements) is inconclusive. Further research into the potential role of diet in early life and the risk of acute leukemia is needed to develop prevention strategies at population level. Review Registration: PROSPERO registration no. CRD42019128937.
000127804 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000127804 590__ $$a4.8$$b2023
000127804 592__ $$a1.301$$b2023
000127804 591__ $$aNUTRITION & DIETETICS$$b18 / 114 = 0.158$$c2023$$dQ1$$eT1
000127804 593__ $$aNutrition and Dietetics$$c2023$$dQ1
000127804 593__ $$aFood Science$$c2023$$dQ1
000127804 594__ $$a9.2$$b2023
000127804 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000127804 700__ $$aBlanco-Lopez, Jessica
000127804 700__ $$0(orcid)0000-0003-4242-5464$$aIguacel, Isabel$$uUniversidad de Zaragoza
000127804 700__ $$aPisanu, Silvia
000127804 700__ $$aAlmeida, Claudia Choma Bettega
000127804 700__ $$aSteliarova-Foucher, Eva
000127804 700__ $$aSierens, Ciska
000127804 700__ $$aGunter, Marc J.
000127804 700__ $$aLadas, Elena J.
000127804 700__ $$aBarr, Ronald D.
000127804 700__ $$aVan Herck, Koen
000127804 700__ $$aKozlakidis, Zisis
000127804 700__ $$aHuybrechts, Inge
000127804 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000127804 773__ $$g15, 17 (2023), 3775 [15 pp.]$$pNutrients$$tNutrients$$x2072-6643
000127804 8564_ $$s822653$$uhttps://zaguan.unizar.es/record/127804/files/texto_completo.pdf$$yVersión publicada
000127804 8564_ $$s2691441$$uhttps://zaguan.unizar.es/record/127804/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000127804 909CO $$ooai:zaguan.unizar.es:127804$$particulos$$pdriver
000127804 951__ $$a2024-11-22-12:04:24
000127804 980__ $$aARTICLE