000127909 001__ 127909
000127909 005__ 20240705134145.0
000127909 0247_ $$2doi$$a10.1038/s41746-023-00876-x
000127909 0248_ $$2sideral$$a135132
000127909 037__ $$aART-2023-135132
000127909 041__ $$aeng
000127909 100__ $$aWillems, Ruben
000127909 245__ $$aCost effectiveness review of text messaging, smartphone application, and website interventions targeting T2DM or hypertension
000127909 260__ $$c2023
000127909 5060_ $$aAccess copy available to the general public$$fUnrestricted
000127909 5203_ $$aDigital health interventions have been shown to be clinically-effective for type 2 diabetes mellitus (T2DM) and hypertension prevention and treatment. This study synthesizes and compares the cost-effectiveness of text-messaging, smartphone application, and websites by searching CINAHL, Cochrane Central, Embase, Medline and PsycInfo for full economic or cost-minimisation studies of digital health interventions in adults with or at risk of T2DM and/or hypertension. Costs and health effects are synthesised narratively. Study quality appraisal using the Consensus on Health Economic Criteria (CHEC) list results in recommendations for future health economic evaluations of digital health interventions. Of 3056 records identified, 14 studies are included (7 studies applied text-messaging, 4 employed smartphone applications, and 5 used websites). Ten studies are cost-utility analyses: incremental cost-utility ratios (ICUR) vary from dominant to €75,233/quality-adjusted life year (QALY), with a median of €3840/QALY (interquartile range €16,179). One study finds no QALY difference. None of the three digital health intervention modes is associated with substantially better cost-effectiveness. Interventions are consistently cost-effective in populations with (pre)T2DM but not in populations with hypertension. Mean quality score is 63.0% (standard deviation 13.7%). Substandard application of time horizon, sensitivity analysis, and subgroup analysis next to transparency concerns (regarding competing alternatives, perspective, and costing) downgrades quality of evidence. In conclusion, smartphone application, text-messaging, and website-based interventions are cost-effective without substantial differences between the different delivery modes. Future health economic studies should increase transparency, conduct sufficient sensitivity analyses, and appraise the ICUR more critically in light of a reasoned willingness-to-pay threshold.
000127909 536__ $$9info:eu-repo/grantAgreement/EC/H2020/945246 /EU/An intersectoral innovative solution involving DIGItal tools, empowering families and integrating community CARE services for the prevention and management of type 2 diabetes and hypertension/DigiCare4You$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 945246 -DigiCare4You
000127909 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000127909 592__ $$a4.273$$b2023
000127909 593__ $$aComputer Science Applications$$c2023$$dQ1
000127909 593__ $$aMedicine (miscellaneous)$$c2023$$dQ1
000127909 593__ $$aHealth Information Management$$c2023$$dQ1
000127909 593__ $$aHealth Informatics$$c2023$$dQ1
000127909 655_4 $$ainfo:eu-repo/semantics/article
000127909 700__ $$aAnnemans, Lieven
000127909 700__ $$aSiopis, George
000127909 700__ $$aMoschonis, George
000127909 700__ $$aVedanthan, Rajesh
000127909 700__ $$aJung, Jenny
000127909 700__ $$aKwasnicka, Dominika
000127909 700__ $$aOldenburg, Brian
000127909 700__ $$ad’Antonio, Claudia
000127909 700__ $$aGirolami, Sandro
000127909 700__ $$aAgapidaki, Eirini
000127909 700__ $$aManios, Yannis
000127909 700__ $$aVerhaeghe, Nick
000127909 700__ $$aUsheva, Natalya
000127909 700__ $$aIotova, Violeta
000127909 700__ $$aTriantafyllidis, Andreas
000127909 700__ $$aVotis, Konstantinos
000127909 700__ $$aToti, Florian
000127909 700__ $$aMakrilakis, Konstantinos
000127909 700__ $$aSeghieri, Chiara
000127909 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, Luis$$uUniversidad de Zaragoza
000127909 700__ $$aDupont, Sabine
000127909 700__ $$aLewis, Leo
000127909 700__ $$aDjokic, Djordje
000127909 700__ $$aSkouteris, Helen
000127909 700__ $$a
000127909 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000127909 773__ $$g6, 150 (2023), 13$$pnpj digit. med.$$tnpj digital medicine$$x2398-6352
000127909 8564_ $$s1300292$$uhttps://zaguan.unizar.es/record/127909/files/texto_completo.pdf
000127909 8564_ $$s2915321$$uhttps://zaguan.unizar.es/record/127909/files/texto_completo.jpg?subformat=icon$$xicon
000127909 909CO $$ooai:zaguan.unizar.es:127909$$particulos$$pdriver
000127909 951__ $$a2024-07-05-12:47:17
000127909 980__ $$aARTICLE