000127956 001__ 127956 000127956 005__ 20240705134210.0 000127956 0247_ $$2doi$$a10.18176/jiaci.0859 000127956 0248_ $$2sideral$$a134090 000127956 037__ $$aART-2023-134090 000127956 041__ $$aeng 000127956 100__ $$0(orcid)0000-0002-9600-8116$$aPaño-Pardo, JR$$uUniversidad de Zaragoza 000127956 245__ $$aManagement of patients with suspected or confirmed antibiotic allergy: executive summary of guidelines from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH)... 000127956 260__ $$c2023 000127956 5060_ $$aAccess copy available to the general public$$fUnrestricted 000127956 5203_ $$aSuspected or confirmed antibiotic allergy is a frequent clinical circumstance that influences antimicrobial prescription and often leads to the avoidable use of less efficacious and/or more toxic or costly drugs than first-line antimicrobials. Optimizing antimicrobial therapy in patients with antibiotic allergy labels has become one of the priorities of antimicrobial stewardship programs in several countries. These guidelines aim to make recommendations for the systematic approach to patients with suspected or confirmed antibiotic allergy based on current evidence. An expert panel (11 members of various scientific societies) formulated questions about the management of patients with suspected or confirmed antibiotic allergy. A systematic literature review was performed by a medical librarian. The questions were distributed among panel members who selected the most relevant references, summarized the evidence, and formulated graded recommendations when possible. The answers to all the questions were finally reviewed by all panel members. A systematic approach to patients with suspected or confirmed antibiotic allergy was recommended to improve antibiotic selection and, consequently, clinical outcomes. A clinically oriented, 3-category risk-stratification strategy was recommended for patients with suspected antibiotic allergy. Complementary assessments should consider both clinical risk category and preferred antibiotic agent. Empirical therapy recommendations for the most relevant clinical syndromes in patients with suspected or confirmed ß-lactam allergy were formulated, as were recommendations on the implementation and monitoring of the impact of the guidelines. Antimicrobial stewardship programs and allergists should design and implement activities that facilitate the most appropriate use of antibiotics in these patients. 000127956 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000127956 592__ $$a0.817$$b2023 000127956 593__ $$aImmunology and Allergy$$c2023$$dQ2 000127956 593__ $$aImmunology$$c2023$$dQ3 000127956 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000127956 700__ $$aMoreno Rodilla, E 000127956 700__ $$aCobo Sacristan, S 000127956 700__ $$aCubero Saldaña, JL$$uUniversidad de Zaragoza 000127956 700__ $$aPeriañez Párraga, L 000127956 700__ $$adel Pozo León, JL 000127956 700__ $$aRetamar-Gentil, P 000127956 700__ $$aRodríguez Oviedo, A 000127956 700__ $$aTorres Jaén, MJ 000127956 700__ $$aVidal-Cortes, P 000127956 700__ $$0(orcid)0000-0001-8959-6784$$aColás Sanz, C$$uUniversidad de Zaragoza 000127956 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000127956 773__ $$g33, 2 (2023), 95-101$$pJ. investig. allergol. clin. immunol.$$tJournal of Investigational Allergology and Clinical Immunology$$x1018-9068 000127956 8564_ $$s427922$$uhttps://zaguan.unizar.es/record/127956/files/texto_completo.pdf$$yVersión publicada 000127956 8564_ $$s2340575$$uhttps://zaguan.unizar.es/record/127956/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000127956 909CO $$ooai:zaguan.unizar.es:127956$$particulos$$pdriver 000127956 951__ $$a2024-07-05-12:51:30 000127956 980__ $$aARTICLE