000129398 001__ 129398
000129398 005__ 20231215094311.0
000129398 0247_ $$2doi$$a10.9734/JAMPS/2020/v22i1030197
000129398 0248_ $$2sideral$$a135487
000129398 037__ $$aART-2020-135487
000129398 041__ $$aeng
000129398 100__ $$aLozano, Roberto
000129398 245__ $$aLow plasma iron levels associated to drug treatment in polymedicated patients: a case-control study
000129398 260__ $$c2020
000129398 5060_ $$aAccess copy available to the general public$$fUnrestricted
000129398 5203_ $$aAim: To identify the drug class and/or duration of treatments causing hyposideremia.
Study Design: Retrospective case-control study.
Place and Duration of Study: Departments of Internal Medicine and Pharmacy, Aragón Health Services Services Hospital Real de Nuestra Señora de Gracia, between January 2019 and December 2019.
Methodology: The records of prescripted medicines of all patients admitted to Internal Medicine service, for various indications, along a 1-year period (2019), which were ultimately analized according to association with hyposideremia.
Results: It was identified several drugs associated with low plasma iron levels: acetylcysteine and apixaban, which would increase the risk of hyposideremia. On the contrary, we found that allopurinol, duloxetine and simvastatin would protect against the appearance of hyposideremia.
Conclusion: Acetylcysteine and apixaban, alone or in combination with different pathologies, would be capable of inducing, and on dependence of the duration of treatment and/or of the concomitant pathology, hyposideremia, iron deficiency and, in certain cases, anemia constituting a major health problem.
000129398 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000129398 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000129398 700__ $$0(orcid)0000-0001-9962-3387$$aFrutos, Alberto$$uUniversidad de Zaragoza
000129398 700__ $$aApesteguía, Alberto
000129398 700__ $$aMartinez, Alejandro
000129398 700__ $$aFranco, María Esther$$uUniversidad de Zaragoza
000129398 700__ $$aAlcazar, María Ángeles
000129398 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000129398 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000129398 773__ $$g22, 10 (2020), 23-28$$pJ. adv. med. pharm. sci.$$tJournal of advances in medical and pharmaceutical sciences$$x2394-1111
000129398 8564_ $$s176361$$uhttps://zaguan.unizar.es/record/129398/files/texto_completo.pdf$$yVersión publicada
000129398 8564_ $$s1565180$$uhttps://zaguan.unizar.es/record/129398/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000129398 909CO $$ooai:zaguan.unizar.es:129398$$particulos$$pdriver
000129398 951__ $$a2023-12-14-13:21:39
000129398 980__ $$aARTICLE