000129468 001__ 129468
000129468 005__ 20241125101124.0
000129468 0247_ $$2doi$$a10.1073/pnas.2304848120
000129468 0248_ $$2sideral$$a135766
000129468 037__ $$aART-2023-135766
000129468 041__ $$aeng
000129468 100__ $$aMu, Wenjie
000129468 245__ $$aScattered differentiation of unlinked loci across the genome underlines ecological divergence of the selfing grass Brachypodium stacei
000129468 260__ $$c2023
000129468 5060_ $$aAccess copy available to the general public$$fUnrestricted
000129468 5203_ $$aEcological divergence without geographic isolation, as an early speciation process that may lead finally to reproductive isolation through natural selection, remains a captivating topic in evolutionary biology. However, the pattern of genetic divergence underlying this process across the genome may vary between species and mating systems. Here, we present evidence that Brachypodium stacei, an annual and highly selfing grass model species, has undergone sympatric ecological divergence without geographic isolation. Genomic, transcriptomic, and metabolomic analyses together with lab experiments mimicking the two opposite environmental conditions suggest that diploid B. stacei populations have diverged sympatrically in two slopes characterized by distinct biomes at Evolution Canyon I (ECI), Mount Carmel, Israel. Despite ongoing gene flow, primarily facilitated by seed dispersal, the level of gene flow has progressively decreased over time. This local adaptation involves the scattered divergence of many unlinked loci across the total genome that include both coding genes and noncoding regions. Additionally, we have identified significant differential expressions of genes related to the ABA signaling pathway and contrasting metabolome composition between the arid- vs. forest-adapted B. stacei populations in ECI. These results suggest that multiple small loci involved in environmental responses act additively to account for ecological adaptations by this selfing species in contrasting environments.
000129468 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FSE/A01-23R$$9info:eu-repo/grantAgreement/ES/DGA/LMP82-21$$9info:eu-repo/grantAgreement/ES/MICINN/PID2019-108195GB-I00
000129468 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000129468 590__ $$a9.4$$b2023
000129468 592__ $$a3.737$$b2023
000129468 591__ $$aMULTIDISCIPLINARY SCIENCES$$b13 / 134 = 0.097$$c2023$$dQ1$$eT1
000129468 593__ $$aMultidisciplinary$$c2023$$dQ1
000129468 594__ $$a19.0$$b2023
000129468 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000129468 700__ $$aLi, Kexin
000129468 700__ $$aYang, Yongzhi
000129468 700__ $$aBreiman, Adina
000129468 700__ $$aLou, Shangling
000129468 700__ $$aYang, Jiao
000129468 700__ $$aWu, Ying
000129468 700__ $$aWu, Shuang
000129468 700__ $$aLiu, Jianquan
000129468 700__ $$aNevo, Eviatar
000129468 700__ $$0(orcid)0000-0001-7793-5259$$aCatalan, Pilar$$uUniversidad de Zaragoza
000129468 7102_ $$15011$$2063$$aUniversidad de Zaragoza$$bDpto. CC.Agrar.y Medio Natural$$cÁrea Botánica
000129468 773__ $$g120, 45 (2023), e2304848120 [9 pp.]$$pProc. Natl. Acad. Sci.$$tProceedings of the National Academy of Sciences of the United States of America$$x0027-8424
000129468 8564_ $$s11320640$$uhttps://zaguan.unizar.es/record/129468/files/texto_completo.pdf$$yVersión publicada
000129468 8564_ $$s3705416$$uhttps://zaguan.unizar.es/record/129468/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000129468 909CO $$ooai:zaguan.unizar.es:129468$$particulos$$pdriver
000129468 951__ $$a2024-11-22-11:57:10
000129468 980__ $$aARTICLE