In vivo biomechanical response of the human cornea to acoustic waves

Ávila, Francisco J. (Universidad de Zaragoza) ; Marcellán, Maria Concepción (Universidad de Zaragoza) ; Remón, Laura (Universidad de Zaragoza)

Resumen: The cornea is the optical window to the brain. Its optical and structural properties are responsible for optical transparency and vision. The shape, elasticity, rigidity, or stiffness are due to its biomechanical properties, whose stability results in ocular integrity and intraocular pressure dynamics. Here, we report in vivo observations of shape changes and biomechanical alterations in the human cornea induced by acoustic wave pressure within the frequency range of 50–350 Hz and the sound pressure level of 90 dB. The central corneal thickness (CCT) and eccentricity (e2) were measured using Scheimpflug imaging and biomechanical properties [corneal hysteresis (CH) and intraocular pressure (IOP)] were assessed with air-puff tonometry in six young, healthy volunteers. At the specific 150 Hz acoustic frequency, the variations in e2 and CCT were 0.058 and 7.33 µm, respectively. Biomechanical alterations were also observed in both the IOP (a decrease of 3.60 mmHg) and CH (an increase of 0.40 mmHg).

Idioma: Inglés

DOI: 10.3390/opt4040043

Año: 2023

Publicado en: Optics (Basel) 4, 4 (2023), 584-594
ISSN: 2673-3269

Factor impacto CITESCORE: 2.2 - Atomic and Molecular Physics, and Optics (Q3) - Physics and Astronomy (miscellaneous) (Q3) - Electronic, Optical and Magnetic Materials (Q3)

Factor impacto SCIMAGO: 0.196 - Atomic and Molecular Physics, and Optics (Q4) - Physics and Astronomy (miscellaneous) (Q4) - Electronic, Optical and Magnetic Materials (Q4)

Financiación: info:eu-repo/grantAgreement/ES/UZ/JIUZ-2021-CIE-01

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Óptica (Dpto. Física Aplicada)