129524 20240731103420.0 doi 10.3390/opt4040043 sideral 135807 ART-2023-135807 eng Ávila, Francisco J. Universidad de Zaragoza (orcid)0000-0002-9068-7728 In vivo biomechanical response of the human cornea to acoustic waves 2023 Access copy available to the general public Unrestricted The cornea is the optical window to the brain. Its optical and structural properties are responsible for optical transparency and vision. The shape, elasticity, rigidity, or stiffness are due to its biomechanical properties, whose stability results in ocular integrity and intraocular pressure dynamics. Here, we report in vivo observations of shape changes and biomechanical alterations in the human cornea induced by acoustic wave pressure within the frequency range of 50–350 Hz and the sound pressure level of 90 dB. The central corneal thickness (CCT) and eccentricity (e2) were measured using Scheimpflug imaging and biomechanical properties [corneal hysteresis (CH) and intraocular pressure (IOP)] were assessed with air-puff tonometry in six young, healthy volunteers. At the specific 150 Hz acoustic frequency, the variations in e2 and CCT were 0.058 and 7.33 µm, respectively. Biomechanical alterations were also observed in both the IOP (a decrease of 3.60 mmHg) and CH (an increase of 0.40 mmHg). info:eu-repo/grantAgreement/ES/UZ/JIUZ-2021-CIE-01 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 0.196 2023 Atomic and Molecular Physics, and Optics 2023 Q4 Physics and Astronomy (miscellaneous) 2023 Q4 Electronic, Optical and Magnetic Materials 2023 Q4 2.2 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Marcellán, Maria Concepción Universidad de Zaragoza (orcid)0000-0002-7516-3029 Remón, Laura Universidad de Zaragoza (orcid)0000-0002-3979-4528 2002 647 Universidad de Zaragoza Dpto. Física Aplicada Área Óptica 4, 4 (2023), 584-594 Optics (Basel) Optics (Basel) 2673-3269 3482827 http://zaguan.unizar.es/record/129524/files/texto_completo.pdf Versión publicada 2663639 http://zaguan.unizar.es/record/129524/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:129524 articulos driver 2024-07-31-10:09:03 ARTICLE