000129633 001__ 129633
000129633 005__ 20240319080955.0
000129633 0247_ $$2doi$$a10.1016/j.archger.2022.104751
000129633 0248_ $$2sideral$$a129838
000129633 037__ $$aART-2022-129838
000129633 041__ $$aeng
000129633 100__ $$0(orcid)0000-0002-0061-3312$$aGómez-Soria, Isabel$$uUniversidad de Zaragoza
000129633 245__ $$aEffects of multi-component non-pharmacological interventions on cognition in participants with mild cognitive impairment: A systematic review and meta-analysis
000129633 260__ $$c2022
000129633 5060_ $$aAccess copy available to the general public$$fUnrestricted
000129633 5203_ $$aBackground and purpose: Mild cognitive impairment (MCI) describes a stage of intermediate cognitive dysfunction where the risk of conversion to dementia is elevated. Given the absence of effective pharmacological treatments for MCI, increasing numbers of studies are attempting to understand how multicomponent non-pharmacological interventions (MNPI) could benefit MCI. The purpose of this systematic review and meta-analysis were to assess the effects of two-component MNPI (simultaneous cognitive intervention based on cognitive stimulation, cognitive training and/or cognitive rehabilitation or combined cognitive and physical interventions) on global cognition and cognitive functions in older adults with MCI and to compare the degree of efficacy between the two interventions. Methods: After searching electronic databases (PubMed, Web of Science, Scopus and Cochrane Central) for randomized controlled trials and clinical trials published from 2010 to 18 January 2021, 562 studies were found. 8 studies were included in this review, with a fair to good quality according to the PEDro scale. Results: From a random-effects model meta-analysis, the pooled standardized MMSE mean difference between the intervention and control groups showed a significant small-to-medium effect in global cognition in MMSE score (0.249; 95% CI = [0.067, 0.431]), which seemed to be greater for combined physical and cognitive interventions. However, the meta-analyses did not show any effects regarding specific cognitive functions. Conclusion: Our analyses support that MNPI could improve the global cognition in older adults with MCI. However, more studies are needed to analyze the potential benefits of MNPI on older adults with MCI.
000129633 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000129633 590__ $$a4.0$$b2022
000129633 591__ $$aGERIATRICS & GERONTOLOGY$$b24 / 54 = 0.444$$c2022$$dQ2$$eT2
000129633 592__ $$a1.008$$b2022
000129633 593__ $$aGerontology$$c2022$$dQ1
000129633 593__ $$aHealth (social science)$$c2022$$dQ1
000129633 593__ $$aAging$$c2022$$dQ2
000129633 593__ $$aGeriatrics and Gerontology$$c2022$$dQ2
000129633 594__ $$a6.8$$b2022
000129633 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/acceptedVersion
000129633 700__ $$0(orcid)0000-0002-1042-542X$$aMarin-Puyalto, Jorge$$uUniversidad de Zaragoza
000129633 700__ $$aPeralta-Marrupe, Patricia$$uUniversidad de Zaragoza
000129633 700__ $$0(orcid)0000-0002-5797-3909$$aLatorre, Eva$$uUniversidad de Zaragoza
000129633 700__ $$0(orcid)0000-0002-4307-796X$$aCalatayud, Estela$$uUniversidad de Zaragoza
000129633 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000129633 7102_ $$11006$$2413$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Fisioterapia
000129633 7102_ $$11002$$2050$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Biología Celular
000129633 773__ $$g103 (2022), 104751 [14 pp.]$$pArch. gerontol. geriatr.$$tARCHIVES OF GERONTOLOGY AND GERIATRICS$$x0167-4943
000129633 8564_ $$s2912014$$uhttps://zaguan.unizar.es/record/129633/files/texto_completo.pdf$$yPostprint
000129633 8564_ $$s1408864$$uhttps://zaguan.unizar.es/record/129633/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000129633 909CO $$ooai:zaguan.unizar.es:129633$$particulos$$pdriver
000129633 951__ $$a2024-03-18-13:30:43
000129633 980__ $$aARTICLE