129814 20240912131721.0 doi 10.22489/CinC.2022.340 sideral 136106 ART-2022-136106 eng Sales Bellés, Clara Universidad de Zaragoza Right ventricular vs left bundle branch pacing-induced changes in ECG depolarization and repolarization 2022 Access copy available to the general public Unrestricted Patients suffering from bradycardia are indicated for pacemaker implantation. Right ventricular pacing (RVP)has been conventionally used for this purpose, but it can increase the risk of atrial fibrillation and heart failure. Left bundle branch area pacing (LBBAP) has been proposed as a new physiological pacing technique. The aim of this study was to compare changes induced by RVP and LBBAP in the ECG. 10-minute 12-lead ECG recordings were acquired at baseline and after pacemaker implantation from 83 patients (31 RVP, 52 LBBAP). Median beats were calculated for each patient at baseline and post-implantation states. ECG markers including QRS duration (dQRS)and area (aQRS) and heart rate-corrected QT (QTc) and Tpeak-to-Tend (Tpec) intervals were measured. dQRS and aQRS decreased significantly at post-implantation with respect to baseline, both being significantly lower for LBBAP than RVP after pacemaker implantation. QTc was significantly reduced at post-implantation for both pacing techniques with no differences between them. Tpec did not change either between states or techniques. In conclusion, LBBAP led to more synchronized ventricular depolarization, supporting potentially improved clinical outcomes with LBBAP as compared to RVP for anti-bradycardia therapy info:eu-repo/grantAgreement/ES/DGA-FSE/T39-20R info:eu-repo/grantAgreement/ES/DGA/LMP94_21 info:eu-repo/grantAgreement/ES/MICINN/PID2019-105674RB-I00 info:eu-repo/grantAgreement/ES/MICINN/RYC2019-027420-I info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 0.212 2022 Computer Science (miscellaneous) 2022 Cardiology and Cardiovascular Medicine 2022 info:eu-repo/semantics/conferenceObject info:eu-repo/semantics/publishedVersion Palacios, Saúl Universidad de Zaragoza (orcid)0000-0001-5935-9454 Melero, Jorge Universidad de Zaragoza Julián, Inés Ramos, Javier Universidad de Zaragoza Pablo Martínez, Juan Universidad de Zaragoza (orcid)0000-0002-7503-3339 Minchole, Ana Universidad de Zaragoza (orcid)0000-0003-3183-4107 Pueyo, Esther Universidad de Zaragoza (orcid)0000-0002-1960-407X 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 5008 800 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Teoría Señal y Comunicac. 49 (2022), [4 pp.] Comput. cardiol. Computing in Cardiology 2325-8861 1072540 http://zaguan.unizar.es/record/129814/files/texto_completo.pdf Versión publicada 2650258 http://zaguan.unizar.es/record/129814/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:129814 articulos driver 2024-09-12-13:15:39 ARTICLE