000129831 001__ 129831
000129831 005__ 20240912131721.0
000129831 0247_ $$2doi$$a10.22489/CinC.2023.316
000129831 0248_ $$2sideral$$a136103
000129831 037__ $$aART-2023-136103
000129831 041__ $$aeng
000129831 100__ $$aSales Bellés, Clara$$uUniversidad de Zaragoza
000129831 245__ $$aLeft Bundle Branch Area Pacing Generates More Physiological Ventricular Activation Sequences than Right Ventricular Pacing
000129831 260__ $$c2023
000129831 5060_ $$aAccess copy available to the general public$$fUnrestricted
000129831 5203_ $$aLeft bundle branch area pacing (LBBAP) has been proposed as a novel physiological pacing modality to overcome ventricular dyssynchrony reported in bradycardic patients who undergo conventional right ventricular pacing (RVP). The standard non-invasive measure of depolarization synchrony is the QRS duration. However, a deeper understanding of not only the activation time but also the activation sequence is required to evaluate the effects of RVP and LBBAP in bradycardic patients. This study aimed to characterize and compare the ventricular activation sequences obtained from both pacing techniques, LBBAP and RVP, by analyzing the standard 12-lead ECGs of bradycardic patients with physiological conduction. 22 RVP and 42 LBBAP ECG recordings were collected before and after pacemaker implantation. High (HF) and low (LF) frequency-based methods for QRS complex analysis were used and the precordial activation sequence and activation delay (pAD) were estimated. Results showed more physiological activation sequences after LBBAP than after RVP, with lower pAD (p<0.01) after LBBAP [HF:12(2,15) vs29(6,56); LF:9(-25,13) vs31(17,38)]. The proposed ECG methodology could be used in clinical practice to map more physiological pacing targets in pacemaker implantation.
000129831 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000129831 592__ $$a0.227$$b2023
000129831 593__ $$aComputer Science (miscellaneous)$$c2023
000129831 593__ $$aCardiology and Cardiovascular Medicine$$c2023
000129831 594__ $$a1.1$$b2023
000129831 655_4 $$ainfo:eu-repo/semantics/conferenceObject$$vinfo:eu-repo/semantics/publishedVersion
000129831 700__ $$0(orcid)0000-0003-3183-4107$$aMincholé, Ana$$uUniversidad de Zaragoza
000129831 700__ $$aMelero, Jorge
000129831 700__ $$aCabrera-Ramos, Mercedes
000129831 700__ $$aMontilla-Padilla, Isabel
000129831 700__ $$aSorinas, Laura
000129831 700__ $$aJulián, Inés
000129831 700__ $$0(orcid)0000-0002-1960-407X$$aPueyo, Esther$$uUniversidad de Zaragoza
000129831 700__ $$aRamos, Javier$$uUniversidad de Zaragoza
000129831 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000129831 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac.
000129831 773__ $$g(2023), [4 pp.]$$pComput. cardiol.$$tComputing in Cardiology$$x2325-8861
000129831 8564_ $$s601743$$uhttps://zaguan.unizar.es/record/129831/files/texto_completo.pdf$$yVersión publicada
000129831 8564_ $$s2672442$$uhttps://zaguan.unizar.es/record/129831/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000129831 909CO $$ooai:zaguan.unizar.es:129831$$particulos$$pdriver
000129831 951__ $$a2024-09-12-13:15:39
000129831 980__ $$aARTICLE