doi:10.1016/j.diabres.2022.109979engMateo Gallego, R.Madinaveitia Nisarre, L.Giné Gonzalez, J.Bea, A. M.Guerra Torrecilla, L.Baila Rueda, L.Pérez Calahorra, S.Civeira, F.Lamiquiz Moneo, I.The effects of high-intensity interval training on glucose metabolism, cardiorespiratory fitness and weight control in subjects with diabetes: systematic review a meta-analysisART-2022-130051Aim: The objective of this meta-analysis was to explore the effects of high-intensity interval training (HIIT) compared with control conditions (CON) or moderate intensity continuous training (MICT) on glycemic parameters in diabetes subjects. Methods: Pubmed, Embase and Google Scholar databases were searched for HIIT interventions that were carried out in diabetic subjects and exploring fasting glucose, glycated haemoglobin (HbA1c), fasting insulin and/or HOMA-IR. Results: This systematic review retrieved a total of 1741 studies of which 32 articles fulfilled the eligibility criteria. Nineteen trials were included in the meta-analysis since they compared HIIT intervention with CON or MICT group. There was a significantly reduction of fasting glucose of 13.3 mg/dL (p < 0.001), Hb1Ac -0.34% (p < 0.001), insulin -2.27 UI/L (p = 0.003), HOMA-IR -0.88 (p = 0.005) in the HIIT-group compared with CON-group. Nevertheless, this reduction was not significantly different when comparing HIIT with MICT (p = 0.140, p = 0.315, p = 0.520 and p = 0.389). Besides, there was a significant increase of absolute VO2max of 0.21 L/min (p < 0.001) and relative VO2max of 2.94 ml/kg/min (p < 0.001) in the HIIT-group compared with the CON-group and the MICT-group (0.22 L/min, p = 0.025) and (0.97 ml/kg/min, p = 0.045). Conclusions: These findings revealed that HIIT intervention led to significant improvement in glycemic control and insulin resistance in subjects with diabetes compared with CON-group.2022http://zaguan.unizar.es/record/12986810.1016/j.diabres.2022.109979http://zaguan.unizar.es/record/129868oai:zaguan.unizar.es:129868info:eu-repo/grantAgreement/ES/DGA/B14-7Rinfo:eu-repo/grantAgreement/ES/MINECO/PI15-01983info:eu-repo/grantAgreement/ES/MINECO/PI18-01777DIABETES RESEARCH AND CLINICAL PRACTICE 190 (2022), 109979 [20 pp.]by-nc-ndhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccess