130025 20250619084224.0 doi 10.1371/journal.pntd.0011087 sideral 136362 ART-2023-136362 eng Ospina-Aguirre, Carolina Effects of human mobility on the spread of Dengue in the region of Caldas, Colombia 2023 Access copy available to the general public Unrestricted According to the World Health Organization (WHO), dengue is the most common acute arthropod-borne viral infection in the world. The spread of dengue and other infectious diseases is closely related to human activity and mobility. In this paper we analyze the effect of introducing mobility restrictions as a public health policy on the total number of dengue cases within a population. To perform the analysis, we use a complex metapopulation in which we implement a compartmental propagation model coupled with the mobility of individuals between the patches. This model is used to investigate the spread of dengue in the municipalities of Caldas (CO). Two scenarios corresponding to different types of mobility restrictions are applied. In the first scenario, the effect of restricting mobility is analyzed in three different ways: a) limiting the access to the endemic node but allowing the movement of its inhabitants, b) restricting the diaspora of the inhabitants of the endemic node but allowing the access of outsiders, and c) a total isolation of the inhabitants of the endemic node. In this scenario, the best simulation results are obtained when specific endemic nodes are isolated during a dengue outbreak, obtaining a reduction of up to 2.5% of dengue cases. Finally, the second scenario simulates a total isolation of the network, i.e., mobility between nodes is completely limited. We have found that this control measure increases the number of total dengue cases in the network by 2.36%. info:eu-repo/grantAgreement/ES/DGA/E36-23R-FENOL info:eu-repo/grantAgreement/ES/MICINN/PID2020-113582GB-I00 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.4 2023 TROPICAL MEDICINE 5 / 28 = 0.179 2023 Q1 T1 PARASITOLOGY 9 / 45 = 0.2 2023 Q1 T1 1.258 2023 Infectious Diseases 2023 Q1 Public Health, Environmental and Occupational Health 2023 Q1 Pharmacology, Toxicology and Pharmaceutics (miscellaneous) 2023 Q1 7.4 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Soriano-Paños, David (orcid)0000-0002-6388-4056 Olivar-Tost, Gerard Galindo-González, Cristian C. Gómez-Gardeñes, Jesús Universidad de Zaragoza (orcid)0000-0001-5204-1937 Osorio, Gustavo 2003 395 Universidad de Zaragoza Dpto. Física Materia Condensa. Área Física Materia Condensada 17, 11 (2023), e0011087 [20 pp.] PLoS negl. trop. dis. PLoS Neglected Tropical Diseases 1935-2727 1326565 http://zaguan.unizar.es/record/130025/files/texto_completo.pdf Versión publicada 2511416 http://zaguan.unizar.es/record/130025/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:130025 articulos driver 2025-06-19-08:41:29 ARTICLE