000130045 001__ 130045 000130045 005__ 20241125101150.0 000130045 0247_ $$2doi$$a10.1016/j.fpsl.2023.101196 000130045 0248_ $$2sideral$$a136321 000130045 037__ $$aART-2023-136321 000130045 041__ $$aeng 000130045 100__ $$0(orcid)0000-0002-0759-9170$$aAznar, Margarita$$uUniversidad de Zaragoza 000130045 245__ $$aDetermination of volatile migrants from breast milk storage bags 000130045 260__ $$c2023 000130045 5060_ $$aAccess copy available to the general public$$fUnrestricted 000130045 5203_ $$aBreast milk storage bags are commonly used to facilitate extended periods of breastfeeding. These bags must meet the necessary safety standards for infant food and comply with current regulations. As they are typically made from polyethylene and feature printing inks on their surface, there is a potential for the transfer of polymer and ink additives, as well as non-intentionally added substances (NIAS), into the milk. An initial study was conducted using two breast milk bags to identify the primary migrants that could be released from this particular food packaging. Migration tests were conducted in both milk and the corresponding food simulant D1 (50% ethanol/water, v/v) under conditions mimicking typical breast milk storage conditions (4–5ºC, 7 days) and defrosting conditions (40ºC, 2 h). The results showed the presence of volatile migrants in both situations, whether long storage periods at refrigerated conditions or brief periods if the temperature is not under control. The outcomes also highlighted that the primary migrants were breakdown products from Irgafos 168, a widely used trisarylphosphite-based antioxidant. These included 2,4-ditertbutylphenol (2,4-dtBP), 1,3-di-tert-butylbenzene (1,3-dtBB), and 2,6-di-tert-butyl-1,4-benzoquinone (2,6-dtBBQ). A subsequent study was carried out involving eight breast milk bags to evaluate the migration of these compounds and to conduct a comprehensive risk assessment of the materials used, ensuring the safety of infants' health is not compromised. Results showed that 1,3-dtBB exceeded the maximum recommended migration values in two of the studied bags. Nevertheless, further toxicity tests are necessary to ensure the safety of these materials in relation to food. 000130045 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/T53-20R$$9info:eu-repo/grantAgreement/ES/MICINN/PID2021-128089OB-I00 000130045 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000130045 590__ $$a8.5$$b2023 000130045 592__ $$a1.468$$b2023 000130045 591__ $$aFOOD SCIENCE & TECHNOLOGY$$b8 / 173 = 0.046$$c2023$$dQ1$$eT1 000130045 593__ $$aBiomaterials$$c2023$$dQ1 000130045 593__ $$aFood Science$$c2023$$dQ1 000130045 593__ $$aSafety, Risk, Reliability and Quality$$c2023$$dQ1 000130045 593__ $$aPolymers and Plastics$$c2023$$dQ1 000130045 593__ $$aMicrobiology (medical)$$c2023$$dQ1 000130045 594__ $$a14.0$$b2023 000130045 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000130045 700__ $$0(orcid)0000-0001-8893-0963$$aDomeño, Celia$$uUniversidad de Zaragoza 000130045 700__ $$0(orcid)0000-0003-2685-5739$$aNerin, Cristina$$uUniversidad de Zaragoza 000130045 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica 000130045 773__ $$g40 (2023), 101196 [9 pp.]$$tFood Packaging and Shelf Life$$x2214-2894 000130045 8564_ $$s906182$$uhttps://zaguan.unizar.es/record/130045/files/texto_completo.pdf$$yVersión publicada 000130045 8564_ $$s2589057$$uhttps://zaguan.unizar.es/record/130045/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000130045 909CO $$ooai:zaguan.unizar.es:130045$$particulos$$pdriver 000130045 951__ $$a2024-11-22-12:06:31 000130045 980__ $$aARTICLE