130073 20240122171020.0 doi 10.1007/s10596-020-09945-6 sideral 117435 ART-2020-117435 eng Sánchez, María Teresa (orcid)0000-0002-3514-6443 The role of fluid flow on bone mechanobiology: mathematical modeling and simulation 2020 The effect of fluid flow on tissue adaptation was the focus of many research works during the last years. Moreover, the use of poroelasticity models to simulate and understand the interstitial flow movement has taken interest due to the possibility to include the fluid effect on mechanical simulations. In particular, shear stresses induced by bone canalicular fluid flow are suggested to be one of the mechanical stimulus controlling bone remodeling processes. Due to the high difficulty to measure canalicular fluid flow and shear stresses, computational poroelastic models can be used in order to estimate these parameters. In this work, a finite element dual porosity model based on Russian doll poroelasticity is developed. Two experiments with a turkey ulna and a human femur are simulated. Bone lacuno-canalicular fluid flow is computed and compared with the experimental results, focusing on the zones of bone remodeling and showing a relation between this flow and the bone formation process. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/MICINN/RTI2018-094494-B-C21 info:eu-repo/grantAgreement/ES/MINECO/DPI2015-64221-C2-1-R info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84780-C2-1-R info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 2.413 2020 GEOSCIENCES, MULTIDISCIPLINARY 115 / 198 = 0.581 2020 Q3 T2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS 67 / 111 = 0.604 2020 Q3 T2 0.695 2020 Computational Mathematics 2020 Q2 Computers in Earth Sciences 2020 Q2 Computer Science Applications 2020 Q2 Computational Theory and Mathematics 2020 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Pérez, María Ángeles Universidad de Zaragoza (orcid)0000-0002-2901-4188 García-Aznar, José Manuel Universidad de Zaragoza (orcid)0000-0002-9864-7683 5004 605 Universidad de Zaragoza Dpto. Ingeniería Mecánica Área Mec.Med.Cont. y Teor.Est. 25 (2020), 823–830 Comput. geosci COMPUTATIONAL GEOSCIENCES 1420-0597 6759606 http://zaguan.unizar.es/record/130073/files/texto_completo.pdf Postprint 2344891 http://zaguan.unizar.es/record/130073/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:130073 articulos driver 2024-01-22-15:24:59 ARTICLE