000130103 001__ 130103 000130103 005__ 20240705134148.0 000130103 0247_ $$2doi$$a10.37201/req/115.2023 000130103 0248_ $$2sideral$$a136493 000130103 037__ $$aART-2023-136493 000130103 041__ $$aeng 000130103 100__ $$aMoreno Guillén, Santiago 000130103 245__ $$aTuberculosis in Spain: an opinion paper 000130103 260__ $$c2023 000130103 5060_ $$aAccess copy available to the general public$$fUnrestricted 000130103 5203_ $$aThis document is the result of the deliberations of the Committee on Emerging Pathogens and COVID-19 of the Illustrious Official College of Physicians of Madrid (ICOMEM) regarding the current situation of tuberculosis, particularly in Spain. We have reviewed aspects such as the evolution of its incidence, the populations currently most exposed and the health care circuits for the care of these patients in Spain. We have also discussed latent tuberculosis, the reality of extrapulmonary disease in the XXI century and the means available in daily practice for the diagnosis of both latent and active forms. The contribution of molecular biology, which has changed the perspective of this disease, was another topic of discussion. The paper tries to put into perspective both the classical drugs and their resistance figures and the availability and indications of the new ones. In addition, the reality of direct observation in the administration of antituberculosis drugs has been discussed. All this revolution is making it possible to shorten the treatment time for tuberculosis, a subject that has also been reviewed. If everything is done well, the risk of relapse of tuberculosis is small but it exists. On the other hand, many special situations have been discussed in this paper, such as tuberculosis in pediatric age and tuberculosis as a cause for concern in surgery and intensive care. The status of the BCG vaccine and its present indications as well as the future of new vaccines to achieve the old dream of eradicating this disease have been discussed. Finally, the ethical and medicolegal implications of this disease are not a minor issue and our situation in this regard has been reviewed. 000130103 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/ 000130103 592__ $$a0.399$$b2023 000130103 593__ $$aMedicine (miscellaneous)$$c2023$$dQ3 000130103 593__ $$aPharmacology$$c2023$$dQ3 000130103 593__ $$aMicrobiology (medical)$$c2023$$dQ3 000130103 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000130103 700__ $$aRodríguez-Artalejo, Fernando 000130103 700__ $$aRuiz-Galiana, Julián 000130103 700__ $$aCantón, Rafael 000130103 700__ $$aDe Lucas Ramos, Pilar 000130103 700__ $$aGarcía-Botella, Alejandra 000130103 700__ $$aGarcía-Lledó, Alberto 000130103 700__ $$aHernández-Sampelayo, Teresa 000130103 700__ $$aGómez-Pavón, Javier 000130103 700__ $$aGonzález del Castillo, Juan 000130103 700__ $$aMartín-Delgado, Mari Cruz 000130103 700__ $$aMartín Sánchez, Francisco Javier 000130103 700__ $$aMartínez-Sellés, Manuel 000130103 700__ $$aMolero García, José María 000130103 700__ $$aSantiago, Begoña 000130103 700__ $$aCaminero, José Antonio 000130103 700__ $$aBarros, Carlos 000130103 700__ $$aGarcía de Viedma, Darío 000130103 700__ $$0(orcid)0000-0003-2993-5478$$aMartín, Carlos$$uUniversidad de Zaragoza 000130103 700__ $$aBouza, Emilio 000130103 7102_ $$11011$$2630$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Microbiología 000130103 773__ $$g36, 6 (2023), 562-583$$pRev. esp. quimioter.$$tRevista española de quimioterapia$$x0214-3429 000130103 8564_ $$s375254$$uhttps://zaguan.unizar.es/record/130103/files/texto_completo.pdf$$yVersión publicada 000130103 8564_ $$s2972284$$uhttps://zaguan.unizar.es/record/130103/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000130103 909CO $$ooai:zaguan.unizar.es:130103$$particulos$$pdriver 000130103 951__ $$a2024-07-05-12:47:53 000130103 980__ $$aARTICLE